Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PurityIn-House HPLC & MS Tested
HormonesSKU: CP-SRM
Sermorelin Acetate
≥99% PurityHPLC & MS verified
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Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of naturally occurring growth hormone-releasing hormone (GHRH). It is one of the most well-characterized GHRH analogs in growth hormone axis research. GHRH(1-29) – bioactive fragment of native GHRH Growth hormone release and pulsatility research Somatotroph axis function studies For research purposes only.
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| 1 unit | €14.99 | €14.99 | -- |
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Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Purity HPLC
99.3% average HPLC purity, verified by independent third-party testing
Third-Party Tested
Janoshik report published when available
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Last reviewed: 2026-04-14
About Sermorelin Acetate
About Sermorelin
Sermorelin (CAS: 86168-78-7) is a synthetic peptide consisting of the first 29 amino acids of the 44-amino acid human growth hormone-releasing hormone (GHRH). This N-terminal fragment retains the full biological activity of the native hormone, as the first 29 residues contain the complete receptor-binding domain. Sermorelin was among the earliest GHRH analogs studied and has an extensive research history spanning over four decades in growth hormone physiology.
Mechanism of Action
Sermorelin binds to the GHRH receptor (GHRHR) on anterior pituitary somatotroph cells, activating adenylyl cyclase through Gs-protein coupling and increasing intracellular cAMP concentrations. This signaling cascade stimulates both the synthesis and secretion of growth hormone (GH) in a pulsatile, physiological manner. Unlike exogenous GH, sermorelin preserves the natural feedback mechanisms of the hypothalamic-pituitary-somatotroph axis, including sensitivity to somatostatin-mediated inhibition, maintaining physiological GH pulsatility.
Published Research
- Gelato, M. C., et al. (1985). Growth hormone responses to growth hormone-releasing hormone (GHRH 1-29) in normal subjects. Journal of Clinical Endocrinology & Metabolism. DOI: 10.1210/jcem-70-1-99
- Merriam, G. R., et al. (2009). Growth hormone-releasing hormone treatment in diagnostic testing and adult GH deficiency. Journal of Clinical Endocrinology & Metabolism. DOI: 10.1210/jc.2009-0048
Product Specifications
- Molecular Weight: 3357.9 Da
- CAS Number: 86168-78-7
- Sequence: GHRH(1-29)NH2
- Purity: 99.3% avg (HPLC)
- Form: Lyophilized powder
- Storage: -20°C, protected from light
View Certificate of Analysis (COA)
This product is intended for laboratory research use only. Not for human consumption. Not a drug, food, or cosmetic. CertaPeptides does not condone or encourage any off-label use.
Specification Summary
Purity99.3% avg
FormLyophilized Powder
Storage-20\u00B0C
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Every batch is independently verified by Janoshik Analytical (100,000+ verifications/month), Eurofins Scientific, and Analytical Sciences International. We publish every Certificate of Analysis.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI RO54451735, VAT-registered. SameDay for Romania, FanCourier for Central/Eastern EU, TCE Worldwide for the rest. 3–7 business days EU-wide.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
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