Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PurityIn-House HPLC & MS Tested
HormonesSKU: CP-HEX
Hexarelin Acetate
≥99% PurityHPLC & MS verified
From €22.99In Stock
Only 10left in stock — order soon
Delivers to EU in 7-10 business days
Free shipping over €200 · no customs paperwork (EU) · via EU carrier network
Hexarelin is a synthetic hexapeptide growth hormone secretagogue and one of the most potent GHS-R1a receptor agonists studied. It has been researched for its strong growth hormone-releasing properties and cardioprotective effects. Potent synthetic GH secretagogue hexapeptide Growth hormone release and axis stimulation Cardiovascular and cardioprotective research For research purposes only.
Volume PricingApplied automatically at checkout
| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €22.99 | €22.99 | -- |
| 3+ | €21.84 | €65.52 | 5% off |
| 5+Most Popular | €20.69 | €103.46 | 10% off |
| 10+ | €19.54 | €195.42 | 15% off |
Size
Please select a size to continue
Earn 22 loyalty points with this purchase
1
Total: €22.99
Free shipping on orders over €200
Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Purity HPLC
99.3% average HPLC purity, verified by independent third-party testing
Third-Party Tested
Janoshik report published when available
Fast Shipping
24h dispatch, EU-wide shipping from €4.99
Third-Party Tested
Independent lab verification for every batch
Last reviewed: 2026-04-18
About Hexarelin Acetate
Hexarelin is His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 — a synthetic hexapeptide GHS-R1a agonist developed as an analog of GHRP-6, with two structural changes that increase receptor binding affinity and metabolic stability. The result is one of the most potent synthetic GHS peptides in terms of GH release per unit dose. Arvat's 1997 comparison study ran hexarelin, GHRP-2, GHRP-6, and GHRH side by side in healthy human subjects. Hexarelin produced the highest GH peak of the group. CAS: 140703-51-1. MW 887.0 Da.
The trade-off for that potency is selectivity. Ipamorelin's value in research is a clean GHS-R1a signal without off-target effects. Hexarelin doesn't offer that — it stimulates modest but measurable increases in prolactin, ACTH, and cortisol alongside GH, a consequence of receptor affinity extending to non-somatotroph populations. For experiments where clean GH-axis isolation matters, that's a limitation. For experiments characterizing the full downstream consequences of potent GHS-R1a activation, it's the relevant profile.
The Cardiac Signal
Beyond the pituitary, hexarelin has a documented GH-independent cardiac activity. It binds CD36 — a scavenger receptor expressed on cardiomyocytes — through a mechanism distinct from GHS-R1a. This cardiac signaling pathway has been studied in ischemia-reperfusion models, where hexarelin shows cardioprotective effects that persist in GH-deficient animals, confirming the effect is independent of GH axis activation. Two independent receptor systems in one compound: the pituitary GHS-R1a signal and the cardiac CD36 signal. Researchers working in GH pharmacology and those studying cardiac peptide biology can both find use here, though the experimental designs needed to isolate each pathway differ substantially.
Specifications
| Molecular Weight | 887.0 Da |
|---|---|
| Sequence | His-D-2-Me-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| CAS | 140703-51-1 |
| Purity | 99.3% avg by HPLC |
| Form | Lyophilized powder |
| Sizes | 2mg, 5mg |
Storage: −20°C, protected from light. Reconstitute in sterile water or 0.1% acetic acid; use within 4 weeks at 4°C.
Quality: HPLC purity analysis, mass spec identity confirmation, endotoxin testing on every batch. COA ships with every order. EU-based QC under CERTALAB S.R.L.
Frequently Asked Questions
What is hexarelin's cardiac mechanism?
Hexarelin binds CD36, a scavenger receptor expressed on cardiomyocytes, independently of GHS-R1a. In ischemia-reperfusion models, this produces cardioprotective effects that persist in GH-deficient animals — confirming the effect is not mediated through GH axis activation. The CD36-binding activity is a distinct pharmacological property of hexarelin not shared by other GHRP family members like GHRP-2, GHRP-6, or ipamorelin.
When would you choose hexarelin over GHRP-2 or ipamorelin?
Hexarelin is the right choice when maximum GH stimulation is the goal and off-target effects are acceptable or part of the experimental question. It's also the appropriate tool for any research on the CD36 cardiac pathway, where neither GHRP-2 nor ipamorelin provides activity. For clean GH research without cortisol or prolactin confounds, ipamorelin is the better choice. For positive controls requiring the highest GH output, hexarelin or GHRP-2 are appropriate depending on how the cortisol/prolactin effects factor into the design.
For research purposes only. Not for human consumption.
Specification Summary
Purity99.3% avg
FormLyophilized Powder
Storage-20\u00B0C
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Every batch is independently verified by Janoshik Analytical (100,000+ verifications/month), Eurofins Scientific, and Analytical Sciences International. We publish every Certificate of Analysis.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI RO54451735, VAT-registered. SameDay for Romania, FanCourier for Central/Eastern EU, TCE Worldwide for the rest. 3–7 business days EU-wide.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
Frequently Asked
Research Library
Related Research Articles
Based on category & popularity
Researchers Also Studied
SAME FIELDHormones
HGH Fragment 176-191
AOD-9604 is a modified peptide fragment corresponding to amino acids 176-191 of human growth hormone, with a tyrosine substitution at the C-terminus. It has been specifically studied for its lipid metabolism pathway signaling independent of growth-promoting effects. Modified hGH fragment (176-191) with C-terminal tyrosine Lipid metabolism pathway and adipose tissue signaling research Lipid metabolism signaling without somatotropic pathway activation For research purposes only.
From€18.99
SAME FIELDHormones
Tesamorelin
Research-grade Tesamorelin. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
From€18.99
SAME FIELDHormones
HCG
Research-grade HCG. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
From€22.99
SAME FIELDHormones
Sermorelin Acetate
Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of naturally occurring growth hormone-releasing hormone (GHRH). It is one of the most well-characterized GHRH analogs in growth hormone axis research. GHRH(1-29) – bioactive fragment of native GHRH Growth hormone release and pulsatility research Somatotroph axis function studies For research purposes only.
From€14.99