Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PurityIn-House HPLC & MS Tested
Copper and Mitochondrial Research PeptidesSKU: CP-MOT
MOTS-c
≥99% PurityHPLC & MS verified
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Research-grade MOTS-c. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
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| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €34.99 | €34.99 | -- |
| 3+ | €33.24 | €99.72 | 5% off |
| 5+Most Popular | €31.49 | €157.46 | 10% off |
| 10+ | €29.74 | €297.42 | 15% off |
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Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Purity HPLC
99.3% average HPLC purity, verified by independent third-party testing
Third-Party Tested
Janoshik report published when available
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24h dispatch, EU-wide shipping from €4.99
Third-Party Tested
Independent lab verification for every batch
Last reviewed: 2026-04-26
About MOTS-c
About MOTS-c
What is MOTS-c?
Here is something that should not exist according to the central dogma: a peptide encoded in mitochondrial DNA that leaves the mitochondria, travels to the nucleus, and directly regulates gene expression. MOTS-c is a 16-amino-acid mitochondrial-derived peptide discovered by Changhan David Lee at USC in 2015, and it acts as a retrograde signal — information flowing from the organelle to the genome, backwards from what textbooks describe.
CAS: 1627580-64-6. The first exercise-mimetic peptide of mitochondrial origin. It activates AMPK, the same pathway that exercise engages.
Mechanism of Action
Why it is interesting
Two things. First, the retrograde signaling: MOTS-c is encoded in mitochondrial 12S rRNA, not the nuclear genome. Under metabolic stress, it translocates to the nucleus and directly regulates transcription. This means your mitochondria are not just energy factories — they are talking to your nucleus, telling it to adjust metabolic gene expression.
Second, the exercise mimicry. MOTS-c activates AMPK by inhibiting de novo purine synthesis, which causes AICAR accumulation — the same endogenous AMPK activator that builds up during exercise. The compound basically trips the same metabolic alarm that physical activity triggers.
Research Overview
Specs
Molecular weight2,174.4 Da
CAS1627580-64-6
Purity99.3% avg by HPLC
FormLyophilized powder
Sizes5mg, 10mg
Storage
Lyophilized at -20°C. Reconstituted: 2-8°C, use within 4 weeks.
Quality
HPLC, mass spec, endotoxin testing. COA included. EU QC under CERTALAB S.R.L.
Product Specifications
- Purity: 99.3% avg (HPLC verified)
- Form: Lyophilized powder
- SKU: CP-MOT
Certificate of Analysis available for every batch. View COAs →
For research purposes only. Not for human consumption.
Specification Summary
Purity99.3% avg
FormLyophilized Powder
Storage-20\u00B0C
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Every batch is independently verified by Janoshik Analytical (100,000+ verifications/month), Eurofins Scientific, and Analytical Sciences International. We publish every Certificate of Analysis.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI RO54451735, VAT-registered. SameDay for Romania, FanCourier for Central/Eastern EU, TCE Worldwide for the rest. 3–7 business days EU-wide.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
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