Compuesto de grado de investigación. Solo para uso en laboratorio. No destinado al uso humano o animal, ni a su ingestión o inyección. No se realiza ni se da a entender ninguna afirmación médica.
Pureza ≥98%Especificación de lote del proveedor · ≥98% (class spec)
Gonadotropic Research PeptidesSKU: CP-TRI2
Triptorelin Acetate 2mg
Pureza ≥98%Especificación del lote del proveedor; lotes seleccionados probados por Janoshik
Referencia de investigación
peptidesdb.org
/p/triptorelin
29,99 €En stock
Solo quedan 10 en stock — pida pronto
Se entrega en EU en 11-14 días hábiles
Envío gratis a partir de €200 · sin trámites aduaneros (UE) · a través de EU carrier network
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Total: 29,99 €
Envío gratis en pedidos superiores a €200
Research-grade Triptorelin Acetate. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
Precios por volumenSe aplica automáticamente al finalizar la compra
| Cantidad | Precio por unidad | Total | Ahorro |
|---|---|---|---|
| 1 unit | 29,99 € | 29,99 € | -- |
| 3+ | 28,49 € | 85,47 € | 5% de descuento |
| 5+Más popular | 26,99 € | 134,95 € | 10% de descuento |
| 10+ | 25,49 € | 254,92 € | 15% de descuento |
Aviso importante
Este producto está destinado únicamente a uso en laboratorio e investigación. No apto para uso humano ni veterinario. Al comprarlo, confirma que este producto se utilizará exclusivamente con fines de investigación in vitro.
Requiere reconstitución
Este péptido se envía liofilizado (polvo seco) y requiere agua bacteriostática para reconstituirlo antes de su uso. El agua BAC se vende por separado.
Cuándo este producto puede no adecuarse a su investigación
- ⚠Si su investigación requiere material de grado GMP para aplicaciones clínicas: los péptidos de grado de investigación no están destinados al uso clínico.
- ⚠Si su laboratorio carece de un almacenamiento en frío adecuado (congelador a -20°C): la estabilidad de este péptido puede verse comprometida a temperaturas más altas.
- ⚠Si su protocolo de estudio requiere estándares de referencia aprobados por la FDA: contacte con la USP o con un proveedor de material de referencia certificado.
Pureza HPLC
Pureza HPLC media del 99.2%, verificada mediante pruebas independientes de terceros
Probado por terceros
El informe de Janoshik se publica cuando está disponible
Envío rápido
Expedición en 24h, envíos a toda la UE desde €4.99
Probado por terceros
Especificación del lote del proveedor en cada producto; informe independiente de Janoshik en lotes seleccionados
Última revisión: 2026-07-03
Acerca de Triptorelin Acetate 2mg
Triptorelin is a GnRH agonist analogue -- a synthetic decapeptide with modifications at positions 6 and 10 of the native GnRH sequence that dramatically increase potency and half-life compared to endogenous GnRH. It is FDA- and EMA-approved for prostate cancer, endometriosis, and central precocious puberty under various brand names. Like all long-acting GnRH agonists, it produces an initial "flare" of LH and FSH (and consequently sex steroids) followed by receptor desensitization and profound gonadotropin suppression -- reducing circulating testosterone in men to castrate levels. Each vial contains 2mg.
The mechanism of action is counterintuitive until the receptor biology is understood. GnRH receptors respond to pulsatile stimulation; continuous high-level agonism from a long-acting analogue causes receptor downregulation and uncoupling from intracellular signaling. After 2-4 weeks of continuous exposure, LH and FSH secretion drops dramatically, and consequently so do testosterone and estradiol. This chemical castration is medically equivalent to surgical castration for testosterone-sensitive conditions.
For research applications, triptorelin is used to study GnRH receptor pharmacology, model hypogonadism (chemical castration models), investigate hormone-sensitive tissue biology in the absence of sex steroids, and as a positive control for GnRH agonist effects. The initial flare followed by suppression pattern also makes it useful for timing-controlled endocrine studies.
Specifications
| Parameter | Value |
|---|---|
| Compound | Triptorelin acetate (GnRH agonist analogue) |
| Amount per Vial | 2mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Storage
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 14 days. Protect from light.
Why does a GnRH agonist suppress testosterone rather than increase it?
This is the paradox of GnRH agonist pharmacology. The pituitary GnRH receptor requires pulsatile stimulation to maintain LH and FSH secretion. When triptorelin provides continuous (rather than pulsatile) stimulation due to its long half-life, GnRH receptors become desensitized -- they downregulate and uncouple from signaling. After 2-4 weeks, LH and FSH secretion drops to very low levels, testosterone follows, and the result is chemical castration. The initial "flare" (a brief period of increased LH/FSH/testosterone before desensitization) is clinically important in prostate cancer because it can temporarily worsen symptoms before suppression begins.
How is triptorelin used to create castration models in research?
In animal research, triptorelin (or other long-acting GnRH agonists) administered at sufficient doses produces reliable hypogonadism -- very low testosterone -- without surgical castration. This "chemical castration" model is useful for studying androgen-dependent processes, testing testosterone replacement or alternative therapies, and investigating testosterone's role in specific physiological systems. After cessation of triptorelin treatment, endogenous testosterone production recovers (unlike surgical castration), making chemical castration models reversible -- useful for before/after study designs.
What is the difference between triptorelin, leuprolide, and goserelin?
All three are GnRH agonist analogues with the same fundamental mechanism of GnRH receptor desensitization and gonadotropin suppression. They differ primarily in modification sites, formulation, and half-life. Triptorelin is available as short-acting (daily injection) and long-acting (monthly/3-monthly depot) formulations. Leuprolide is similar with multiple depot options. Goserelin is formulated exclusively as a subcutaneous implant. For research, the short-acting daily-injection form of triptorelin or leuprolide allows better dose control than depot formulations, where the release kinetics add variability.
Triptorelin is supplied for laboratory research use only. Not approved for general human use outside of licensed therapeutic indications. Handle in compliance with institutional biosafety guidelines.
Resumen de la especificación
Pureza99.2% avg
FormaPolvo liofilizado
Almacenamiento-20\u00B0C
Acerca de Triptorelin Acetate 2mg
Triptorelin is a GnRH agonist analogue -- a synthetic decapeptide with modifications at positions 6 and 10 of the native GnRH sequence that dramatically increase potency and half-life compared to endogenous GnRH. It is FDA- and EMA-approved for prostate cancer, endometriosis, and central precocious puberty under various brand names. Like all long-acting GnRH agonists, it produces an initial "flare" of LH and FSH (and consequently sex steroids) followed by receptor desensitization and profound gonadotropin suppression -- reducing circulating testosterone in men to castrate levels. Each vial contains 2mg.
The mechanism of action is counterintuitive until the receptor biology is understood. GnRH receptors respond to pulsatile stimulation; continuous high-level agonism from a long-acting analogue causes receptor downregulation and uncoupling from intracellular signaling. After 2-4 weeks of continuous exposure, LH and FSH secretion drops dramatically, and consequently so do testosterone and estradiol. This chemical castration is medically equivalent to surgical castration for testosterone-sensitive conditions.
For research applications, triptorelin is used to study GnRH receptor pharmacology, model hypogonadism (chemical castration models), investigate hormone-sensitive tissue biology in the absence of sex steroids, and as a positive control for GnRH agonist effects. The initial flare followed by suppression pattern also makes it useful for timing-controlled endocrine studies.
Specifications
| Parameter | Value |
|---|---|
| Compound | Triptorelin acetate (GnRH agonist analogue) |
| Amount per Vial | 2mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Storage
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 14 days. Protect from light.
Why does a GnRH agonist suppress testosterone rather than increase it?
This is the paradox of GnRH agonist pharmacology. The pituitary GnRH receptor requires pulsatile stimulation to maintain LH and FSH secretion. When triptorelin provides continuous (rather than pulsatile) stimulation due to its long half-life, GnRH receptors become desensitized -- they downregulate and uncouple from signaling. After 2-4 weeks, LH and FSH secretion drops to very low levels, testosterone follows, and the result is chemical castration. The initial "flare" (a brief period of increased LH/FSH/testosterone before desensitization) is clinically important in prostate cancer because it can temporarily worsen symptoms before suppression begins.
How is triptorelin used to create castration models in research?
In animal research, triptorelin (or other long-acting GnRH agonists) administered at sufficient doses produces reliable hypogonadism -- very low testosterone -- without surgical castration. This "chemical castration" model is useful for studying androgen-dependent processes, testing testosterone replacement or alternative therapies, and investigating testosterone's role in specific physiological systems. After cessation of triptorelin treatment, endogenous testosterone production recovers (unlike surgical castration), making chemical castration models reversible -- useful for before/after study designs.
What is the difference between triptorelin, leuprolide, and goserelin?
All three are GnRH agonist analogues with the same fundamental mechanism of GnRH receptor desensitization and gonadotropin suppression. They differ primarily in modification sites, formulation, and half-life. Triptorelin is available as short-acting (daily injection) and long-acting (monthly/3-monthly depot) formulations. Leuprolide is similar with multiple depot options. Goserelin is formulated exclusively as a subcutaneous implant. For research, the short-acting daily-injection form of triptorelin or leuprolide allows better dose control than depot formulations, where the release kinetics add variability.
Triptorelin is supplied for laboratory research use only. Not approved for general human use outside of licensed therapeutic indications. Handle in compliance with institutional biosafety guidelines.
Confianza del investigador
Por qué los investigadores eligen CertaPeptides
¿Quién prueba esto realmente?
Los lotes seleccionados son verificados de forma independiente por Janoshik Analytical (República Checa) y se publican en el portal público de Janoshik. Los demás lotes se envían con la especificación del lote del proveedor. Consulte /coa para ver el muro publicado.
Ver COA →¿Qué ocurre si recibo el lote equivocado?
La etiqueta de cada frasco lleva un número de lote que corresponde a un certificado de análisis específico. Si un lote no cumple la especificación, no lo enviamos; sin excepciones.
Ver COA →¿Desde dónde se envía?
Rumanía (UE). Somos CERTALAB SRL, CUI 54169956, registrada a efectos de IVA. Sameday para Rumanía, GLS para la mayoría de los destinos de la UE, TCE Worldwide para los demás mercados transfronterizos de la UE y fuera de la UE (Reino Unido, Suiza, Noruega, Islandia, Israel, Serbia). Entrega en 1–15 días hábiles según el destino; el plazo exacto se muestra al finalizar la compra.
Detalles de envío →¿Qué ocurre si hay un problema?
Dispone de un derecho de desistimiento de 14 días en virtud de la OUG 34/2014 (legislación rumana/de la UE en materia de consumo), con posibilidad de escalado a la ANPC/ODR. Contáctenos en support@certapeptides.com.
Política de devoluciones →Información del producto
Este producto está destinado únicamente a fines de investigación y desarrollo científicos. Es una sustancia química que no debe utilizarse como fármaco, medicamento, principio activo ni ingrediente en ningún producto destinado al consumo humano o animal. Los investigadores deben manipular este compuesto de acuerdo con las directrices de bioseguridad de su institución. Utilícese únicamente en entornos de laboratorio debidamente equipados y con el equipo de protección individual adecuado.
Preguntas frecuentes
Biblioteca de investigación
Artículos de investigación relacionados
Investigados juntos con frecuencia
Triptorelin Acetate 2mg29,99 €
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