Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PurityIn-House HPLC & MS Tested
Copper and Mitochondrial Research PeptidesSKU: CP-SS31
SS-31
≥99% PurityHPLC & MS verified
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Research-grade SS-31. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
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Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Purity HPLC
99.3% average HPLC purity, verified by independent third-party testing
Third-Party Tested
Janoshik report published when available
Fast Shipping
24h dispatch, EU-wide shipping from €4.99
Third-Party Tested
Independent lab verification for every batch
Last reviewed: 2026-04-23
About SS-31
About SS-31
What is SS-31?
Most antioxidants float around the cytoplasm and scavenge free radicals after they have already been produced. SS-31 goes to where the radicals are made. It concentrates about 1,000-fold in the inner mitochondrial membrane, binds cardiolipin — a phospholipid found only in mitochondria — and stabilizes the electron transport chain so fewer radicals get produced in the first place. Prevention, not cleanup.
CAS: 736992-21-5. Also called elamipretide, Bendavia, and MTP-131. Multiple preclinical and experimental studies have been conducted in the context of Barth syndrome, cardiac biology, and renal biology.
Mechanism of Action
The cardiolipin angle
Cardiolipin is unique to mitochondrial inner membranes. It holds cytochrome c in the right position for efficient electron transfer. When cardiolipin gets oxidized (which happens during aging and in various biological conditions), the electron transport chain becomes sloppy — electrons leak, produce superoxide, damage more cardiolipin, and the cycle accelerates. SS-31 breaks that cycle by stabilizing the cardiolipin-cytochrome c interaction.
Mechanism
The D-Arg-Dmt-Lys-Phe-NH2 sequence has alternating aromatic and cationic residues that drive 1,000-fold mitochondrial accumulation. Once there, it binds cardiolipin, optimizes cytochrome c interaction, reduces electron leak, lowers superoxide production, and maintains ATP output under stress. It also prevents mitochondrial permeability transition pore opening during ischemia-reperfusion — which is why it is studied in cardiac and renal research models.
Research Overview
Experimental interest is significant: Barth syndrome is a genetic cardiolipin deficiency, and SS-31 has been extensively studied in the context of this condition.
Research context
Mitochondrial dysfunction and bioenergetics. Ischemia-reperfusion research (heart, kidney, brain). Age-related mitochondrial decline. Barth syndrome and cardiolipin biology. Cardiac biology and cardiomyopathy research. This is one of the more extensively studied peptides in the catalog — the experimental data is substantial.
Specs
Molecular weight639.8 Da
CAS736992-21-5
Purity99.3% avg by HPLC
FormLyophilized powder
Sizes5mg, 10mg
Product Specifications
- Purity: 99.3% avg (HPLC verified)
- Form: Lyophilized powder
- SKU: CP-SS31
Certificate of Analysis available for every batch. View COAs →
For research purposes only. Not for human consumption.
Specification Summary
Purity99.3% avg
FormLyophilized Powder
Storage-20\u00B0C
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Every batch is independently verified by Janoshik Analytical (100,000+ verifications/month), Eurofins Scientific, and Analytical Sciences International. We publish every Certificate of Analysis.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI RO54451735, VAT-registered. SameDay for Romania, FanCourier for Central/Eastern EU, TCE Worldwide for the rest. 3–7 business days EU-wide.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
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