Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PurityIn-House HPLC & MS Tested
GLP-1 and Incretin Research PeptidesSKU: CP-SLU
SLU-PP-332
≥99% PurityHPLC & MS verified
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Research-grade SLU-PP-332. 99.3% avg purity, HPLC & MS verified. Oral tablets in sealed bottle. For laboratory research use only. Not for human consumption.
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| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €74.99 | €74.99 | -- |
| 3+ | €71.24 | €213.72 | 5% off |
| 5+Most Popular | €67.49 | €337.46 | 10% off |
| 10+ | €63.74 | €637.42 | 15% off |
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Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Purity HPLC
99.3% average HPLC purity, verified by independent third-party testing
Third-Party Tested
Janoshik report published when available
Fast Shipping
24h dispatch, EU-wide shipping from €4.99
Third-Party Tested
Independent lab verification for every batch
Last reviewed: 2026-04-22
About SLU-PP-332
SLU-PP-332 is a small molecule ERRalpha/ERRgamma agonist developed at Saint Louis University as a pharmacological tool for the estrogen-related receptor (ERR) pathway. ERRalpha and ERRgamma are orphan nuclear receptors -- so called because they lack identified endogenous ligands -- that regulate mitochondrial biogenesis, oxidative phosphorylation, and fatty acid metabolism. Before SLU-PP-332, selective ERR agonists were not available, limiting the ability to study ERR pharmacology without genetic manipulation.
The exercise mimetic framing comes from what ERR activation does in practice: it drives many of the same transcriptional programs as endurance exercise -- PGC-1alpha-dependent mitochondrial biogenesis, increased expression of oxidative enzymes, and fiber type shifts toward slow-twitch oxidative phenotypes. This pathway is one of several being investigated for exercise mimetic pharmacology alongside AMPK activators (like AICAR) and Rev-Erbalpha agonists (like SR9009). Having three compounds that engage overlapping but mechanistically distinct pathways allows researchers to determine which aspects of exercise-induced metabolic adaptation are pathway-specific versus convergent.
SLU-PP-332's small molecule structure (MW 490.6 Da) gives it oral bioavailability, distinguishing it from peptide exercise mimetics that require injection. This property makes it suitable for chronic oral dosing studies -- an advantage for protocols studying mitochondrial adaptation over weeks rather than hours.
Research Applications
SLU-PP-332 is used in research on ERR nuclear receptor pharmacology, mitochondrial biogenesis and dynamics, exercise physiology and metabolic adaptation, obesity and cardiovascular disease models, and comparative exercise mimetic studies alongside AMPK and Rev-Erb pathway compounds.
Specifications
| Parameter | Value |
|---|---|
| Compound | SLU-PP-332 (ERRalpha/ERRgamma agonist) |
| Molecular Weight | 490.6 Da |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | DMSO; then aqueous vehicle for oral or IP administration |
| Storage | -20°C, protect from light |
Storage
Store lyophilized powder at -20°C. For reconstituted solutions, prepare fresh or store at 4°C for short-term use. Protect from light throughout.
What does SLU-PP-332 actually do to mitochondria?
SLU-PP-332 activates ERRalpha and ERRgamma nuclear receptors, which in turn drive expression of genes involved in mitochondrial biogenesis and oxidative metabolism. Key downstream effects include increased PGC-1alpha coactivation, upregulation of oxidative phosphorylation enzymes, enhanced fatty acid oxidation, and shifts in muscle fiber type toward slow-twitch oxidative phenotypes. In animal models, chronic SLU-PP-332 treatment has produced improvements in exercise endurance and metabolic parameters -- effects consistent with what you would see after a sustained endurance training program.
How does SLU-PP-332 compare to AICAR for exercise mimetic research?
AICAR activates AMPK (AMP-activated protein kinase), a cellular energy sensor that triggers metabolic adaptation when cellular energy is low. SLU-PP-332 acts through ERR nuclear receptors, which are downstream of PGC-1alpha and more directly regulate mitochondrial gene expression. The two pathways converge on some of the same outcomes (mitochondrial biogenesis, fatty acid oxidation) but through different signaling routes. Using both in parallel allows researchers to dissect which exercise adaptations require AMPK signaling versus those driven by nuclear receptor transcriptional reprogramming.
Is SLU-PP-332 powder the same compound as the capsule version?
Yes, both contain the same SLU-PP-332 compound. The powder form is the lyophilized bulk compound requiring weighing and dissolution before use -- suitable for injection protocols (intraperitoneal or subcutaneous) or for researchers preparing their own oral vehicles. The capsule format pre-doses 100mg per capsule for standardized oral administration without weighing. Choice depends on protocol: injection studies or custom doses favor powder; standardized chronic oral dosing favors capsules.
SLU-PP-332 is supplied for laboratory research use only. Not approved for human use. Handle in compliance with institutional biosafety guidelines.
Specification Summary
Purity99.3% avg
FormLyophilized Powder
Storage-20\u00B0C
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Every batch is independently verified by Janoshik Analytical (100,000+ verifications/month), Eurofins Scientific, and Analytical Sciences International. We publish every Certificate of Analysis.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI RO54451735, VAT-registered. SameDay for Romania, FanCourier for Central/Eastern EU, TCE Worldwide for the rest. 3–7 business days EU-wide.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
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