Semax + Selank Blend 20mg

Semax + Selank Blend combines two Russian-developed nootropic peptides with different but complementary mechanisms in a single vial (10mg each, 20mg total). Both were developed by the Institute of Molecular Genetics of the Russian Academy of Sciences and have been used clinically in Russia and Eastern Europe -- an unusual distinction that provides some human pharmacology data, even if the clinical literature predates modern trial standards.

Semax is a synthetic heptapeptide derived from the ACTH(4-7) sequence with a methionine-glutamate-histidine-phenylalanine extension that increases its stability and bioactivity. It acts primarily through BDNF and NGF pathways -- upregulating brain-derived and nerve growth factors. Research effects include neuroprotection, acetylcholinergic and neuropeptidergic receptor binding in memory consolidation models, and attention-related parameters. Semax has been used in Russian clinical practice for ischemic stroke recovery, which provides some translational context, though the evidence base is not equivalent to Western Phase III trial standards.

Selank is derived from tuftsin, an endogenous immunoregulatory peptide, with a GABA-B receptor component that gives it anxiolytic properties. It modulates GABA system activity and reduces anxiety-like behavior in rodent models without the sedation or dependence potential associated with benzodiazepines. Selank also has immunomodulatory properties and has been studied for stress-induced immune suppression in animal models.

The combination addresses both acetylcholinergic and neuropeptidergic receptor binding (Semax) and anxiety/stress modulation (Selank) -- complementary rather than redundant mechanisms in the context of cognitive performance research.

Specifications

Storage

Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 28 days. Both peptides are stable under proper conditions but should be protected from light and heat.

Semax + Selank Blend is supplied for laboratory research use only. Not approved for human use. Handle in compliance with institutional biosafety guidelines.