Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PurityJanoshik Verified
Copper and Mitochondrial Research PeptidesSKU: CP-GHK
GHK-Cu
≥99% PurityHPLC & MS verified
Janoshik Verified
99.42% HPLC
Report #136726
From €49.99In Stock
Delivers to EU in 7-10 business days
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GHK-Cu is a naturally occurring copper-binding tripeptide (Glycyl-L-histidyl-L-lysine copper complex) studied extensively in tissue biology and cellular remodeling research. Concentration declines with age, making it a key compound in age-related biological studies. Supplied at 99.3% avg purity (HPLC-verified), with Certificate of Analysis for every batch. Key research areas: Tissue remodeling and extracellular matrix pathways Collagen and decorin synthesis stimulation Gene expression modulation (over 4,000 genes identified) For research purposes only. Not for human consumption.
Volume PricingApplied automatically at checkout
| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €49.99 | €49.99 | -- |
| 3+ | €47.49 | €142.47 | 5% off |
| 5+Most Popular | €44.99 | €224.95 | 10% off |
| 10+ | €42.49 | €424.92 | 15% off |
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Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
When This Product May Not Suit Your Research
- ⚠If your research requires a non-metallopeptide — GHK-Cu contains a copper(II) ion integral to its structure.
- ⚠If your assay is sensitive to metal interference — the copper ion may interfere with certain spectrophotometric methods.
- ⚠If you need a peptide with extensive human clinical trial data — GHK-Cu's clinical evidence is primarily from topical applications.
Purity HPLC
99.3% average HPLC purity, verified by independent third-party testing
Janoshik Verified
View report #136726 on janoshik.com →
Fast Shipping
24h dispatch, EU-wide shipping from €4.99
Third-Party Tested
Independent lab verification for every batch
Last reviewed: 2026-04-26
About GHK-Cu
About GHK-Cu
GHK-Cu (CAS 49557-75-7) is a tripeptide-copper complex first isolated from human plasma by Dr. Loren Pickart in 1973. Endogenous plasma concentrations decline from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60, a reduction that correlates with diminished tissue remodeling capacity. This naturally occurring peptide has become one of the most studied compounds in regenerative biology and gene expression research.
Mechanism of Action
GHK-Cu functions as a biological signaling molecule that binds copper(II) ions with high affinity, facilitating copper delivery to enzymatic processes essential for tissue maintenance. The peptide activates TGF-beta and VEGF signaling pathways, stimulating fibroblast proliferation, collagen I/III synthesis, and glycosaminoglycan production. Gene expression studies using the Connectivity Map database have identified GHK as a modulator of over 4,000 human genes.
Published Research
- Gene expression modulation: Connectivity Map analysis identified GHK as capable of resetting the expression of 4,048 genes toward a profile associated with healthy tissue maintenance. (DOI)
- Tissue biology and collagen synthesis: Research demonstrated that GHK-Cu promoted tissue remodeling and increased collagen synthesis, antioxidant enzyme levels, and blood vessel formation. (DOI)
- Tissue remodeling: A comprehensive review detailed how GHK-Cu promotes extracellular matrix remodeling by stimulating synthesis of collagen, decorin, elastin, and glycosaminoglycans. (DOI)
Product Specifications
- Purity: 99.3% avg (HPLC verified)
- Form: Lyophilized powder
- CAS: 49557-75-7
- Molecular Weight: 403.9 Da
Certificate of Analysis available for every batch. View COAs →
Third-party heavy metals + purity report: Janoshik Analytical Report #136727 (GHK-Cu 50mg) — independent lead, mercury, arsenic, cadmium analysis + HPLC purity verification by a Czech ISO-accredited laboratory.
For research purposes only. Not for human consumption.
Specification Summary
Purity99.3% avg
FormLyophilized Powder
Storage-20\u00B0C
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Every batch is independently verified by Janoshik Analytical (100,000+ verifications/month), Eurofins Scientific, and Analytical Sciences International. We publish every Certificate of Analysis.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI RO54451735, VAT-registered. SameDay for Romania, FanCourier for Central/Eastern EU, TCE Worldwide for the rest. 3–7 business days EU-wide.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
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