Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PuritySupplier batch spec · ≥98% (class spec)Sale
Endocrine and Hormone Research PeptidesSKU: CP-GH2
GHRP-2 Acetate
≥98% PuritySupplier batch spec; selected lots Janoshik-tested
Related PeptidesDB entry (same owner)
peptidesdb.org
/p/ghrp-2
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Size5mg
€22.99€25.49
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Total: €22.99
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Research-grade GHRP-2 Acetate. ≥98% supplier batch specification; selected lots independently tested (99.3% avg across published reports). Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
Reconstitution Required
This peptide ships lyophilized (dry powder) and requires bacteriostatic water to reconstitute before use. BAC water is sold separately.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Purity HPLC
99.2% average HPLC purity, verified by independent third-party testing
Third-Party Tested
Janoshik report published when available
Fast Shipping
24h dispatch, EU-wide shipping from €4.99
Third-Party Tested
Supplier batch specification on every product; independent Janoshik report on selected lots
Last reviewed: 2026-07-11
About GHRP-2 Acetate
GHRP-2 (Pralmorelin) is a synthetic hexapeptide GHS-R1a agonist — among the first-generation GHRPs, it is studied for the strongest GH release per unit dose in research models. That potency is the reason it became the standard positive control in GH release assays. CAS: 158861-67-7. MW 817.9 Da. Decades of published data across multiple species and administration routes. If you need a well-characterized GHSR agonist with the widest published dataset, GHRP-2 is it.
Potency vs. Selectivity
In research models, GHRP-2 produces larger GH pulses than ipamorelin, but with less receptor selectivity. At the pituitary, it activates both GHS-R1a (GH release) and ACTH pathways, associated with elevated cortisol in research models. Prolactin rises mildly at higher doses. These off-target hormonal effects are the reason ipamorelin displaced GHRP-2 in protocols where clean GH release without cortisol confounding is required.
The off-targets are not always a problem. If the research question involves GHS-R pharmacology across pituitary cell types, ACTH axis cross-talk, or full characterization of ghrelin receptor signaling, those effects are part of the data. GHRP-2 is more useful than ipamorelin for those questions precisely because it is less selective. Comparison with GHRP-6 is also worth noting: GHRP-2 gives more GH per unit dose in research models; GHRP-6 is studied for stronger appetite stimulation through hypothalamic GHS-R activation.
Specifications
| Molecular Weight | 817.9 Da |
|---|---|
| CAS | 158861-67-7 |
| Purity | ≥98% (supplier batch spec; 99.3% avg across independently tested lots) |
| Form | Lyophilized powder |
| Sizes | 5mg, 10mg |
Storage: Lyophilized: −20°C, away from light. Once reconstituted: 2–8°C, use within 4 weeks.
Quality: Every product ships to a ≥98% supplier batch specification; selected lots are independently tested by Janoshik Analytical (HPLC + mass spectrometry; 99.3% average purity across published reports), searchable by batch code at certapeptides.com/verify. EU-based QC under CERTALAB S.R.L.
Frequently Asked Questions
How does GHRP-2 compare to ipamorelin?
In research models, GHRP-2 produces more GH per unit dose but has less receptor selectivity — it is associated with raised cortisol and prolactin alongside GH. Ipamorelin is selective for somatotroph GHS-R1a with minimal cortisol or prolactin effect. For clean GH axis research, ipamorelin is preferred. For experiments studying full GHS-R pharmacology, ACTH cross-talk, or comparative secretagogue potency, GHRP-2's broader activity profile is the relevant one.
Why is GHRP-2 used as a positive control in GH assays?
GHRP-2 (Pralmorelin) produces reliable, strong GH responses that have been extensively validated across species and administration routes. The consistent, high-amplitude GH release makes it a dependable benchmark for comparing other secretagogues or for confirming that a GH secretion model is working correctly. Its established use as a GHS-R reference agonist further characterized the expected GH response range across research models.
For research purposes only. Not for human consumption.
Specification Summary
Purity99.2% avg
FormLyophilized Powder
Storage-20\u00B0C
About GHRP-2 Acetate
GHRP-2 (Pralmorelin) is a synthetic hexapeptide GHS-R1a agonist — among the first-generation GHRPs, it is studied for the strongest GH release per unit dose in research models. That potency is the reason it became the standard positive control in GH release assays. CAS: 158861-67-7. MW 817.9 Da. Decades of published data across multiple species and administration routes. If you need a well-characterized GHSR agonist with the widest published dataset, GHRP-2 is it.
Potency vs. Selectivity
In research models, GHRP-2 produces larger GH pulses than ipamorelin, but with less receptor selectivity. At the pituitary, it activates both GHS-R1a (GH release) and ACTH pathways, associated with elevated cortisol in research models. Prolactin rises mildly at higher doses. These off-target hormonal effects are the reason ipamorelin displaced GHRP-2 in protocols where clean GH release without cortisol confounding is required.
The off-targets are not always a problem. If the research question involves GHS-R pharmacology across pituitary cell types, ACTH axis cross-talk, or full characterization of ghrelin receptor signaling, those effects are part of the data. GHRP-2 is more useful than ipamorelin for those questions precisely because it is less selective. Comparison with GHRP-6 is also worth noting: GHRP-2 gives more GH per unit dose in research models; GHRP-6 is studied for stronger appetite stimulation through hypothalamic GHS-R activation.
Specifications
| Molecular Weight | 817.9 Da |
|---|---|
| CAS | 158861-67-7 |
| Purity | ≥98% (supplier batch spec; 99.3% avg across independently tested lots) |
| Form | Lyophilized powder |
| Sizes | 5mg, 10mg |
Storage: Lyophilized: −20°C, away from light. Once reconstituted: 2–8°C, use within 4 weeks.
Quality: Every product ships to a ≥98% supplier batch specification; selected lots are independently tested by Janoshik Analytical (HPLC + mass spectrometry; 99.3% average purity across published reports), searchable by batch code at certapeptides.com/verify. EU-based QC under CERTALAB S.R.L.
Frequently Asked Questions
How does GHRP-2 compare to ipamorelin?
In research models, GHRP-2 produces more GH per unit dose but has less receptor selectivity — it is associated with raised cortisol and prolactin alongside GH. Ipamorelin is selective for somatotroph GHS-R1a with minimal cortisol or prolactin effect. For clean GH axis research, ipamorelin is preferred. For experiments studying full GHS-R pharmacology, ACTH cross-talk, or comparative secretagogue potency, GHRP-2's broader activity profile is the relevant one.
Why is GHRP-2 used as a positive control in GH assays?
GHRP-2 (Pralmorelin) produces reliable, strong GH responses that have been extensively validated across species and administration routes. The consistent, high-amplitude GH release makes it a dependable benchmark for comparing other secretagogues or for confirming that a GH secretion model is working correctly. Its established use as a GHS-R reference agonist further characterized the expected GH response range across research models.
For research purposes only. Not for human consumption.
What research shows
Selected peer-reviewed studies from the published literature. Each describes laboratory or preclinical findings and is attributed to the cited study, not to this product. For research use only — not medical guidance.
[1]
Growth hormone secretion
In GH-deficient little mice, GHRP-2 was studied for its ability to stimulate a growth hormone response in preclinical research.
Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient little mice. Clinics (2012). PMID: 22473409[2]
Feeding / orexigenic signalling
In two strains of rats, the ghrelin analogue GHRP-2 stimulated food intake in a dose-dependent manner in in-vivo research.
Regulation of ghrelin gene expression in stomach and feeding response to a ghrelin analogue in two strains of rats. Peptides (2004). PMID: 15572207[3]
Anti-inflammatory effects
In rats, the ghrelin agonist GHRP-2 was associated with attenuation of lipopolysaccharide-induced acute lung injury in preclinical research.
Growth hormone releasing peptide-2, a ghrelin agonist, attenuates lipopolysaccharide-induced acute lung injury in rats. Tohoku Journal of Experimental Medicine (2010). PMID: 20805679Citations are provided for research reference. CertaPeptides (CERTALAB S.R.L.) is a reseller, not a manufacturer, and makes no medical, therapeutic, or efficacy claims. Products are for laboratory research use only and are not for human or animal consumption.
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Selected lots are independently verified by Janoshik Analytical (Czech Republic) and published on the Janoshik public portal. Other lots ship with the supplier's batch specification. See /coa for the published wall.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI 54169956, VAT-registered. Sameday for Romania, GLS for most EU destinations, TCE Worldwide for the remaining cross-border EU and non-EU markets (UK, Switzerland, Norway, Iceland, Israel, Serbia). Delivery 1–15 business days depending on destination — exact window shown at checkout.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
Frequently Asked
Research Library
Related Research Articles
Frequently researched together
GHRP-2 Acetate€22.99