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Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.

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Research-grade Vesugen. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
MADE TO ORDER — Expected delivery: ~3 weeks
Synthesized after your order is placed. We'll email you tracking details when it ships.
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Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
99.3% average HPLC purity, verified by independent third-party testing
Janoshik report published when available
24h dispatch, EU-wide shipping from €4.99
Independent lab verification for every batch
Vesugen is a tripeptide (Lys-Glu-Asp / KED) targeting vascular endothelium — the single-cell layer lining blood vessels that governs vascular permeability, tone, coagulation, and inflammatory signaling. Endothelial dysfunction is an early marker of cardiovascular disease and a central feature of vascular aging: reduced eNOS activity, increased inflammatory adhesion molecule expression, impaired vasodilation. These changes precede overt cardiovascular disease by years in aging populations.
Vesugen shares its KED sequence with Ovagen (ovarian tissue target). In the Khavinson framework, the same sequence reaching vascular endothelial cells is proposed to interact with a different set of available promoter sites than in ovarian tissue, producing tissue-specific effects through cellular context rather than sequence alone. Published research examines eNOS expression, inflammatory cytokine profiles (VCAM-1, ICAM-1), and age-related changes in vascular endothelial function in preclinical models. As with other Khavinson compounds, most published data comes from the Saint Petersburg Institute.
| Sequence | Lys-Glu-Asp (KED) |
|---|---|
| Molecular Weight | ~375 Da (tripeptide) |
| Purity | 99.3% avg by HPLC |
| Form | Lyophilized powder |
| Sizes | 20mg |
Storage: Lyophilized: −20°C, away from light. Once reconstituted: 2–8°C, use within 4 weeks.
Quality: HPLC purity analysis, mass spec identity confirmation, endotoxin testing on every batch. COA ships with every order. EU-based QC under CERTALAB S.R.L.
Endothelial dysfunction — reduced eNOS activity, increased inflammatory adhesion molecule expression, impaired vasodilation — is an early and central feature of cardiovascular disease and vascular aging. Endothelial cells have highly specific gene expression programs (eNOS, von Willebrand factor, endothelin-1, VCAM-1, ICAM-1) that change with age and disease. Short peptide modulation of those programs, if effective, would represent a tissue-level intervention approach distinct from systemic pharmacology.
Published Khavinson work examines eNOS expression, inflammatory cytokine profiles (particularly VCAM-1 and ICAM-1 as markers of endothelial activation), and age-related changes in vascular endothelial function in preclinical models. Nitric oxide production and vasodilatory capacity are the primary functional endpoints of interest in endothelial aging research.
For research purposes only. Not for human consumption.
Researcher Confidence
Who actually tests this?
Every batch is independently verified by Janoshik Analytical (100,000+ verifications/month), Eurofins Scientific, and Analytical Sciences International. We publish every Certificate of Analysis.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI RO54451735, VAT-registered. SameDay for Romania, FanCourier for Central/Eastern EU, TCE Worldwide for the rest. 3–7 business days EU-wide.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
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