Crystagen 20mg

Crystagen is a dipeptide (Glu-Trp / EW) from the Khavinson series with an unusual primary target: the crystalline lens of the eye. The lens is biologically unique — it is avascular, cannot replace lost cells, and its proteins (crystallins) must function for an entire lifetime without turnover. Cataract formation is fundamentally a protein aggregation problem in aging lens tissue. The research question Crystagen addresses: whether short peptide bioregulation can influence gene expression in lens epithelial cells to maintain crystallin protein integrity or delay age-related lens changes.

The Glu-Trp (EW) dipeptide also appears in immune research contexts within the Khavinson framework, making Crystagen one of the more versatile compounds in the series. Lens epithelial cells regulate lens homeostasis through tissue-specific genes — anti-oxidative pathways, crystallin protein expression, and membrane transport. The Khavinson group has published on gene expression changes in lens tissue, with interest in the oxidative stress pathways that accelerate protein aggregation and cataract formation. BBB crossing is not a concern for ocular research — local administration routes are typical.

Specifications

Storage: Lyophilized: −20°C, away from light. Once reconstituted: 2–8°C, use within 4 weeks.

Quality: HPLC purity analysis, mass spec identity confirmation, endotoxin testing on every batch. COA ships with every order. EU-based QC under CERTALAB S.R.L.

For research purposes only. Not for human consumption.