Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
PT-141 10mg
3–7 days most of the EU · 8–14 Nordics/Baltics
Standard EU from €4.99 (RO) · core EU GLS €17.99 · Nordics/Baltics €12.99–€13.99 · Same-day dispatch before 14:00 CET on weekdays · Free shipping over €200 · no customs paperwork (EU) · via EU carrier network
€200.00 away from free shipping over €200. Under that, standard EU shipping is €17.99 (GLS, most of the EU).
How Paysera and SEPA work
- Pay — approve a SEPA transfer in your own bank via Paysera’s hosted page, or send a manual SEPA transfer using the IBAN we email you.
- We confirm — Paysera notifies us instantly, or we match a manual transfer when it arrives (usually 1 business day).
- We dispatch — confirmed orders placed before 14:00 CET on a weekday typically ship the same day.
Card payments are not currently offered. There is no card processor on this checkout.
Free shipping on orders over €200
Research-grade PT-141. ≥98% supplier batch specification; selected lots independently tested. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €41.99 | €41.99 | -- |
| 3+ | €39.89 | €119.67 | 5% off |
| 5+Most Popular | €37.79 | €188.96 | 10% off |
| 10+ | €35.69 | €356.91 | 15% off |
Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
Reconstitution Required
This peptide ships lyophilized (dry powder) and requires bacteriostatic water to reconstitute before use. BAC water is sold separately.
Recommended: BAC water · stable for 28 days at 2-8°C once mixed.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Published laboratory reports are available for selected lots. Check each report for its result and stated method. For research purposes only.
View report #212166 on janoshik.com →
24h dispatch, EU-wide shipping from €4.99
Supplier batch specification on every product; independent Janoshik report on selected lots
About PT-141 10mg
About PT-141 10mg
What is PT-141?
PT-141 (bremelanotide) acts on central melanocortin signalling rather than on peripheral vasculature. That distinction matters mechanistically. PDE5 inhibitors act on blood flow to peripheral tissue -- a vascular, mechanical pathway. PT-141 activates melanocortin-3 and melanocortin-4 receptors in the hypothalamus, modulating arousal circuitry at the level of central nervous system signaling. Different pathway, different mechanism.
CAS: 189691-06-3. Bremelanotide is a centrally-acting melanocortin peptide that has been characterized for its MC3R/MC4R pharmacology.
Mechanism of Action
The melanocortin connection
PT-141 is a derivative of Melanotan II, but with narrower receptor selectivity. MT-II hits MC1R through MC5R and drives pigmentation, appetite, and sexual-arousal pathways all at once. PT-141 was engineered to focus primarily on MC3R/MC4R in the hypothalamic arousal circuitry, with minimal melanogenic activity. It is the difference between a shotgun and a rifle.
Mechanism
MC3R and MC4R agonism in hypothalamic nuclei. These receptors are part of the melanocortin system -- the same pathway that regulates appetite, energy balance, and pigmentation. The arousal-related component involves melanocortin-dopamine crosstalk in reward circuitry. Notably, there is no nitric oxide or PDE5 involvement, which is why PT-141 acts through a completely different mechanism than the PDE5-inhibitor compound class.
Research Overview
Specs
Molecular weight1,025.2 Da
CAS189691-06-3
Purity≥98% supplier batch spec
FormLyophilized powder
Sizes10mg
Storage
Lyophilized at -20°C. Reconstituted: 2-8°C, use within 4 weeks.
Quality
Shipped to a ≥98% supplier batch specification; selected lots are independently tested by Janoshik Analytical, searchable by batch code at certapeptides.com/verify. EU QC under CERTALAB S.R.L.
Product Specifications
- Purity: ≥98% (supplier batch spec)
- Form: Lyophilized powder
- SKU: CP-P41
Selected lots are independently tested by Janoshik Analytical, searchable by batch code at certapeptides.com/verify. View reports →
For research purposes only. Not for human consumption.
Specification Summary
About PT-141 10mg
About PT-141 10mg
What is PT-141?
PT-141 (bremelanotide) acts on central melanocortin signalling rather than on peripheral vasculature. That distinction matters mechanistically. PDE5 inhibitors act on blood flow to peripheral tissue -- a vascular, mechanical pathway. PT-141 activates melanocortin-3 and melanocortin-4 receptors in the hypothalamus, modulating arousal circuitry at the level of central nervous system signaling. Different pathway, different mechanism.
CAS: 189691-06-3. Bremelanotide is a centrally-acting melanocortin peptide that has been characterized for its MC3R/MC4R pharmacology.
Mechanism of Action
The melanocortin connection
PT-141 is a derivative of Melanotan II, but with narrower receptor selectivity. MT-II hits MC1R through MC5R and drives pigmentation, appetite, and sexual-arousal pathways all at once. PT-141 was engineered to focus primarily on MC3R/MC4R in the hypothalamic arousal circuitry, with minimal melanogenic activity. It is the difference between a shotgun and a rifle.
Mechanism
MC3R and MC4R agonism in hypothalamic nuclei. These receptors are part of the melanocortin system -- the same pathway that regulates appetite, energy balance, and pigmentation. The arousal-related component involves melanocortin-dopamine crosstalk in reward circuitry. Notably, there is no nitric oxide or PDE5 involvement, which is why PT-141 acts through a completely different mechanism than the PDE5-inhibitor compound class.
Research Overview
Specs
Molecular weight1,025.2 Da
CAS189691-06-3
Purity≥98% supplier batch spec
FormLyophilized powder
Sizes10mg
Storage
Lyophilized at -20°C. Reconstituted: 2-8°C, use within 4 weeks.
Quality
Shipped to a ≥98% supplier batch specification; selected lots are independently tested by Janoshik Analytical, searchable by batch code at certapeptides.com/verify. EU QC under CERTALAB S.R.L.
Product Specifications
- Purity: ≥98% (supplier batch spec)
- Form: Lyophilized powder
- SKU: CP-P41
Selected lots are independently tested by Janoshik Analytical, searchable by batch code at certapeptides.com/verify. View reports →
For research purposes only. Not for human consumption.
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Selected lots are independently verified by Janoshik Analytical (Czech Republic) and published on the Janoshik public portal. Other lots ship with the supplier's batch specification. See /coa for the published wall.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI 54169956, VAT-registered. Sameday for Romania, GLS for most EU destinations, TCE Worldwide for the remaining cross-border EU and non-EU markets (UK, Switzerland, Iceland, Serbia). Delivery 1–15 business days depending on destination — exact window shown at checkout.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
