Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
MOTS-c
Free shipping on orders over €200
- If a product doesn't match the specification on its published COA, contact us with your batch number: we investigate against the lot's report and replace any product that fails it, at no cost to you.
- Contact us within 48 hours of delivery with photos of the outer box, inner packing, and any affected vials with labels legible. Confirmed transit damage is replaced at no cost to you.
3–7 days most of the EU · 10–14 Nordics/Baltics
Standard EU from €4.99 (RO) · core EU GLS €17.99 · Nordics/Baltics €12.99–€15.99 · Dispatched within 1–2 business days · Free shipping over €200.00 · no customs paperwork (EU) · via EU carrier network
€200.00 away from free shipping over €200.00. Under that, standard EU shipping is €17.99 (GLS, most of the EU).
How Paysera and SEPA work
- Pay: send a manual SEPA transfer using the IBAN we email you, or, where checkout offers it for your address, approve a SEPA transfer in your own bank via Paysera's hosted page.
- We confirm — Paysera notifies us instantly, or we match a manual transfer when it arrives (usually 1 business day).
- We dispatch — confirmed orders typically ship within 1–2 business days.
Card payments are not currently offered. There is no card processor on this checkout.
Research-grade MOTS-c. Class-level specification ≥98%; selected lots independently tested. Lyophilized powder in sealed glass vial. For research purposes only. Not for human consumption.
| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €41.99 | €41.99 | -- |
| 3+ | €39.89 | €119.67 | 5% off |
| 5+Most Popular | €37.79 | €188.96 | 10% off |
| 10+ | €35.69 | €356.91 | 15% off |
Important Notice
This product is intended for research purposes only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
Due to legal and regulatory requirements, this product cannot be shipped to: Croatia, Italy, Poland, Portugal, Slovenia, and Sweden.
Reconstitution Required
This peptide ships lyophilized (dry powder) and requires bacteriostatic water to reconstitute before use. BAC water is sold separately.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Published laboratory reports are available for selected lots. Check each report for its result and stated method. For research purposes only.
View report #155230 on janoshik.com →
Dispatched within 1–2 business days, shipping from €4.99 in Romania, from €12.99 across the rest of Europe
Class-level specification on record; independent Janoshik report on selected lots
About MOTS-c
About MOTS-c
What is MOTS-c?
Here is something that should not exist according to the central dogma: a peptide encoded in mitochondrial DNA that leaves the mitochondria, travels to the nucleus, and directly regulates gene expression. MOTS-c is a 16-amino-acid mitochondrial-derived peptide discovered by Changhan David Lee at USC in 2015, and it acts as a retrograde signal — information flowing from the organelle to the genome, backwards from what textbooks describe.
CAS: 1627580-64-6. MOTS-c is a mitochondrial-derived peptide studied in laboratory models of AMPK signalling.
Mechanism of Action
Why it is interesting
Two things. First, the retrograde signaling: MOTS-c is encoded in mitochondrial 12S rRNA, not the nuclear genome. Under metabolic stress, it translocates to the nucleus and directly regulates transcription. This means mitochondria are not just energy factories — they signal to the nucleus, adjusting metabolic gene expression.
Second, AMPK signalling. In laboratory models, MOTS-c is reported to activate AMPK by inhibiting de novo purine synthesis.
Research Overview
Storage
Lyophilized at -20°C. Reconstituted: 2-8°C.
Quality
Class-level specification ≥98%; selected lots are independently tested by Janoshik Analytical, searchable by batch or report code at certapeptides.com/verify. Sold and shipped from the EU by CERTALAB S.R.L.
Product Specifications
- Molecular weight: 2,174.6 Da
- CAS: 1627580-64-6
- Purity: ≥98% (class-level specification)
- Form: Lyophilized powder
- SKU: CP-MOT
Selected lots independently tested by Janoshik Analytical, searchable by batch or report code. View reports →
For research purposes only. Not for human consumption.
Specification Summary
About MOTS-c
About MOTS-c
What is MOTS-c?
Here is something that should not exist according to the central dogma: a peptide encoded in mitochondrial DNA that leaves the mitochondria, travels to the nucleus, and directly regulates gene expression. MOTS-c is a 16-amino-acid mitochondrial-derived peptide discovered by Changhan David Lee at USC in 2015, and it acts as a retrograde signal — information flowing from the organelle to the genome, backwards from what textbooks describe.
CAS: 1627580-64-6. MOTS-c is a mitochondrial-derived peptide studied in laboratory models of AMPK signalling.
Mechanism of Action
Why it is interesting
Two things. First, the retrograde signaling: MOTS-c is encoded in mitochondrial 12S rRNA, not the nuclear genome. Under metabolic stress, it translocates to the nucleus and directly regulates transcription. This means mitochondria are not just energy factories — they signal to the nucleus, adjusting metabolic gene expression.
Second, AMPK signalling. In laboratory models, MOTS-c is reported to activate AMPK by inhibiting de novo purine synthesis.
Research Overview
Storage
Lyophilized at -20°C. Reconstituted: 2-8°C.
Quality
Class-level specification ≥98%; selected lots are independently tested by Janoshik Analytical, searchable by batch or report code at certapeptides.com/verify. Sold and shipped from the EU by CERTALAB S.R.L.
Product Specifications
- Molecular weight: 2,174.6 Da
- CAS: 1627580-64-6
- Purity: ≥98% (class-level specification)
- Form: Lyophilized powder
- SKU: CP-MOT
Selected lots independently tested by Janoshik Analytical, searchable by batch or report code. View reports →
For research purposes only. Not for human consumption.
Related research reading
Objective comparisons and research guides covering this compound. Reference material, for research purposes only.
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Selected lots are independently verified by Janoshik Analytical (Czech Republic) and published on the Janoshik public portal. Other lots ship with the supplier's batch specification. See /coa for the published wall.
View COAs →What if I get the wrong batch?
Every vial label carries a code. Look it up on our Verify page: it shows what CertaPeptides publishes for that code and, for a withdrawn lot, that the lot was withdrawn and why. If yours is withdrawn, or if the code on your label finds nothing, email us that code.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI 54169956, VAT-registered. Sameday for Romania, GLS for most EU destinations, TCE Worldwide for the remaining cross-border EU and non-EU markets (UK, Switzerland). Delivery 1–15 business days depending on destination — exact window shown at checkout.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with escalation to ANPC and alternative dispute resolution (SAL) available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
