Offrez 15% de réduction, gagnez 10% sur chaque commande qu'il passe.
Composé de qualité recherche. Usage exclusivement en laboratoire. Non destiné à un usage humain ou animal, à l'ingestion ou à l'injection. Aucune allégation médicale n'est formulée ni sous-entendue.
Livraison en EU sous 11-14 jours ouvrés
Livraison gratuite au-delà de €200 · aucune formalité douanière (UE) · via EU carrier network
Livraison gratuite pour les commandes de plus de €200
Research-grade Adamax. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
| Quantité | Prix unitaire | Total | Économies |
|---|---|---|---|
| 1 unit | 129,99 € | 129,99 € | -- |
| 3+ | 123,49 € | 370,47 € | 5% de réduction |
| 5+Le plus populaire | 116,99 € | 584,96 € | 10% de réduction |
| 10+ | 110,49 € | 1 104,92 € | 15% de réduction |
Avis important
Ce produit est destiné uniquement à un usage de laboratoire et de recherche. Ne convient pas à un usage humain ou vétérinaire. En procédant à l'achat, vous confirmez que ce produit sera utilisé exclusivement à des fins de recherche in vitro.
Reconstitution requise
Ce peptide est expédié lyophilisé (poudre sèche) et nécessite de l'eau bactériostatique pour être reconstitué avant utilisation. L'eau BAC est vendue séparément.
99.2% de pureté HPLC moyenne, vérifiée par des tests indépendants réalisés par un tiers
Rapport Janoshik publié dès qu'il est disponible
Expédition sous 24h, livraison dans toute l'UE à partir de €4.99
Spécification de lot fournisseur sur chaque produit ; rapport Janoshik indépendant sur des lots sélectionnés
Adamax is a synthetic neuropeptide fragment based on the vasopressin analogue family, designed with modifications for improved CNS activity and stability. It is used in cognitive neuroscience research, particularly in memory consolidation and retrieval studies. The vasopressin-related peptides have a long history in memory research going back to the 1970s, when DeWied's group showed that vasopressin and its fragments influence avoidance learning and memory in rodents through CNS mechanisms distinct from vasopressin's peripheral endocrine roles (antidiuretic, vasoconstrictor).
Adamax's research context is the posterior pituitary neuropeptide family -- vasopressin (AVP) and oxytocin -- which have extensive CNS projections distinct from their pituitary hormonal release. These neuropeptides modulate hippocampal and amygdalar circuits relevant to memory encoding, social recognition memory, and stress responses. Modified short-chain fragments of vasopressin (like VP4-8, the parent compound of the adamax family) retain memory-influencing properties with reduced peripheral hormonal effects, making them more useful for isolating CNS cognitive effects.
Research applications include spatial and associative memory studies in rodents, investigations into vasopressin system contributions to CNS receptor binding markers, stress-memory interactions, and as a positive control for vasopressin-family peptide research.
| Parameter | Value |
|---|---|
| Compound | Adamax (vasopressin-derived cognitive nootropic peptide) |
| Amount per Vial | 5mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 28 days. Stable lyophilized for 24+ months under proper storage.
The connection between vasopressin and memory originates from work by David DeWied and colleagues in the 1970s-80s, who showed that vasopressin administered peripherally or centrally improved performance in avoidance learning tests in rats, while vasopressin-deficient (Brattleboro) rats showed memory impairments that could be reversed by vasopressin treatment. Subsequent work identified that short fragments of vasopressin (particularly C-terminal fragments like VP4-8) retained memory-facilitating properties without peripheral hormonal effects, suggesting these effects were mediated by CNS receptors. This research tradition led to development of modified fragments like those in the adamax family.
Vasopressin V1a receptors are expressed in the hippocampus, amygdala, septum, and other limbic structures involved in memory encoding and consolidation. Vasopressin acts as a neuromodulator in these circuits, influencing synaptic plasticity and the encoding of emotionally significant or aversive events. It enhances memory consolidation for avoidance tasks and influences social recognition memory through amygdala V1a signaling. The stress-memory interaction is also relevant: vasopressin release during stress may help encode stress-related memories, which connects vasopressin research to PTSD-related neuroscience.
Common tasks include passive avoidance (one-trial learning with a foot shock), active avoidance, Morris water maze (spatial memory), novel object recognition, and social recognition memory. These tasks have established sensitivity to vasopressin-system interventions. The passive avoidance test is particularly associated with the DeWied vasopressin memory literature because vasopressin fragments robustly improve retention in this paradigm. For researchers studying memory peptides, choosing the appropriate behavioral assay for the memory system of interest (hippocampus-dependent, amygdala-dependent, etc.) is important for interpretable results.
Adamax is supplied for laboratory research use only. Not approved for human use. Handle in compliance with institutional biosafety guidelines.
Adamax is a synthetic neuropeptide fragment based on the vasopressin analogue family, designed with modifications for improved CNS activity and stability. It is used in cognitive neuroscience research, particularly in memory consolidation and retrieval studies. The vasopressin-related peptides have a long history in memory research going back to the 1970s, when DeWied's group showed that vasopressin and its fragments influence avoidance learning and memory in rodents through CNS mechanisms distinct from vasopressin's peripheral endocrine roles (antidiuretic, vasoconstrictor).
Adamax's research context is the posterior pituitary neuropeptide family -- vasopressin (AVP) and oxytocin -- which have extensive CNS projections distinct from their pituitary hormonal release. These neuropeptides modulate hippocampal and amygdalar circuits relevant to memory encoding, social recognition memory, and stress responses. Modified short-chain fragments of vasopressin (like VP4-8, the parent compound of the adamax family) retain memory-influencing properties with reduced peripheral hormonal effects, making them more useful for isolating CNS cognitive effects.
Research applications include spatial and associative memory studies in rodents, investigations into vasopressin system contributions to CNS receptor binding markers, stress-memory interactions, and as a positive control for vasopressin-family peptide research.
| Parameter | Value |
|---|---|
| Compound | Adamax (vasopressin-derived cognitive nootropic peptide) |
| Amount per Vial | 5mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 28 days. Stable lyophilized for 24+ months under proper storage.
The connection between vasopressin and memory originates from work by David DeWied and colleagues in the 1970s-80s, who showed that vasopressin administered peripherally or centrally improved performance in avoidance learning tests in rats, while vasopressin-deficient (Brattleboro) rats showed memory impairments that could be reversed by vasopressin treatment. Subsequent work identified that short fragments of vasopressin (particularly C-terminal fragments like VP4-8) retained memory-facilitating properties without peripheral hormonal effects, suggesting these effects were mediated by CNS receptors. This research tradition led to development of modified fragments like those in the adamax family.
Vasopressin V1a receptors are expressed in the hippocampus, amygdala, septum, and other limbic structures involved in memory encoding and consolidation. Vasopressin acts as a neuromodulator in these circuits, influencing synaptic plasticity and the encoding of emotionally significant or aversive events. It enhances memory consolidation for avoidance tasks and influences social recognition memory through amygdala V1a signaling. The stress-memory interaction is also relevant: vasopressin release during stress may help encode stress-related memories, which connects vasopressin research to PTSD-related neuroscience.
Common tasks include passive avoidance (one-trial learning with a foot shock), active avoidance, Morris water maze (spatial memory), novel object recognition, and social recognition memory. These tasks have established sensitivity to vasopressin-system interventions. The passive avoidance test is particularly associated with the DeWied vasopressin memory literature because vasopressin fragments robustly improve retention in this paradigm. For researchers studying memory peptides, choosing the appropriate behavioral assay for the memory system of interest (hippocampus-dependent, amygdala-dependent, etc.) is important for interpretable results.
Adamax is supplied for laboratory research use only. Not approved for human use. Handle in compliance with institutional biosafety guidelines.
La confiance des chercheurs
Qui teste réellement ce produit ?
Les lots sélectionnés sont vérifiés de manière indépendante par Janoshik Analytical (République tchèque) et publiés sur le portail public de Janoshik. Les autres lots sont expédiés avec la spécification de lot du fournisseur. Consultez /coa pour le mur publié.
Voir les COA →Et si je reçois le mauvais lot ?
Chaque étiquette de flacon porte un numéro de lot qui correspond à un certificat d'analyse spécifique. Si un lot n'est pas conforme à la spécification, nous ne l'expédions pas — un point c'est tout.
Voir les COA →D'où le produit est-il expédié ?
Roumanie (UE). Nous sommes CERTALAB SRL, CUI 54169956, immatriculée à la TVA. Sameday pour la Roumanie, GLS pour la plupart des destinations de l'UE, TCE Worldwide pour les autres marchés transfrontaliers de l'UE et hors UE (Royaume-Uni, Suisse, Norvège, Islande, Israël, Serbie). Livraison sous 1–15 jours ouvrés selon la destination — le délai exact est indiqué lors du passage à la caisse.
Détails de l'expédition →Et en cas de problème ?
Vous disposez d'un droit de rétractation de 14 jours en vertu de l'OUG 34/2014 (droit de la consommation roumain/UE), avec possibilité de recours auprès de l'ANPC/ODR. Contactez-nous à support@certapeptides.com.
Politique de retour →Ce produit est destiné uniquement à des fins de recherche et de développement scientifiques. Il s'agit d'une substance chimique qui ne doit pas être utilisée comme médicament, produit thérapeutique, substance active ou ingrédient dans un quelconque produit destiné à la consommation humaine ou animale. Les chercheurs doivent manipuler ce composé conformément aux directives de biosécurité de leur établissement. À utiliser uniquement dans des environnements de laboratoire correctement équipés, avec un équipement de protection individuelle approprié.