Research-grade compound. Laboratory use only. Not intended for human or animal use, ingestion, or injection. No medical claims are made or implied.
≥98% PuritySupplier batch spec · ≥98% (class spec)
Cyclic and Neuropeptide Research CompoundsSKU: CP-DSIP
DSIP
≥98% PuritySupplier batch spec; selected lots Janoshik-tested
Related PeptidesDB entry (same owner)
peptidesdb.org
/p/dsip
Delivers to EU in 3-7 business days
Free shipping over €200 · no customs paperwork (EU) · via EU carrier network
Size2mg
€14.49
1
Total: €14.49
Free shipping on orders over €200
Research-grade DSIP. ≥98% supplier batch specification; selected lots independently tested (99.3% avg across published reports). Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
Volume PricingApplied automatically at checkout
| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €14.49 | €14.49 | -- |
| 3+ | €13.77 | €41.30 | 5% off |
| 5+Most Popular | €13.04 | €65.21 | 10% off |
| 10+ | €12.32 | €123.16 | 15% off |
Important Notice
This product is intended for laboratory and research use only. Not for human or veterinary use. By purchasing, you confirm this product will be used exclusively for in-vitro research purposes.
Reconstitution Required
This peptide ships lyophilized (dry powder) and requires bacteriostatic water to reconstitute before use. BAC water is sold separately.
Recommended: BAC water · stable for 14 days at 2-8°C once mixed.
When This Product May Not Suit Your Research
- ⚠If your research requires GMP-grade material for clinical applications — research-grade peptides are not intended for clinical use.
- ⚠If your lab lacks proper cold storage (-20°C freezer) — this peptide's stability may be compromised at higher temperatures.
- ⚠If your study protocol requires FDA-approved reference standards — contact USP or a certified reference material provider.
Purity HPLC
99.2% average HPLC purity, verified by independent third-party testing
Third-Party Tested
Janoshik report published when available
Fast Shipping
24h dispatch, EU-wide shipping from €4.99
Third-Party Tested
Supplier batch specification on every product; independent Janoshik report on selected lots
Last reviewed: 2026-07-18
About DSIP
About DSIP
What is DSIP?
Delta Sleep-Inducing Peptide is a nine-amino-acid peptide first pulled from the cerebral venous blood of rabbits during slow-wave sleep in 1977. The name is slightly misleading — DSIP does not simply knock you out. It modulates sleep architecture, specifically promoting delta wave (stage 3/4 NREM) activity without suppressing REM. That is a very different thing from sedation.
CAS: 62568-57-4. A neuromodulatory peptide that sits at an unusual intersection: sleep science, stress physiology, and pain research, all in one compound.
Mechanism of Action
What makes it odd
DSIP does not fit neatly into any single category. It modulates sleep, but also reduces stress-induced ACTH and cortisol. It has analgesic properties through endogenous opioid facilitation. It affects thermoregulation. And it stimulates LH release, which is a completely different axis. Most peptides do one thing well. DSIP touches five different systems, and nobody has fully explained how a nonapeptide manages that.
Mechanism
Promotes delta wave sleep without suppressing REM — it changes sleep quality, not just sleep quantity. Reduces ACTH and cortisol under stress. Facilitates endogenous opioid activity for analgesic effects. Modulates hypothalamic temperature regulation. Stimulates LH through an unclear pituitary mechanism. The multi-system profile suggests DSIP works upstream of these individual effects, possibly at the level of hypothalamic coordination.
Research Overview
Specs
Molecular weight848.8 Da
CAS62568-57-4
Purity≥98% (supplier batch spec; 99.3% avg across independently tested lots)
FormLyophilized powder
Sizes2mg, 5mg
Storage
Lyophilized at -20°C. Reconstituted: 2-8°C, use within 4 weeks.
Quality
Shipped to a ≥98% supplier batch specification; selected lots are independently tested by Janoshik Analytical (HPLC + mass spectrometry; 99.3% average purity across published reports), searchable by batch code at certapeptides.com/verify. EU QC under CERTALAB S.R.L.
Product Specifications
- Purity: ≥98% (supplier batch spec; 99.3% avg across independently tested lots)
- Form: Lyophilized powder
- SKU: CP-DSIP
Selected lots are independently tested and searchable by batch code. Verify a batch →
For research purposes only. Not for human consumption.
Specification Summary
Purity99.2% avg
FormLyophilized Powder
Storage-20\u00B0C
About DSIP
About DSIP
What is DSIP?
Delta Sleep-Inducing Peptide is a nine-amino-acid peptide first pulled from the cerebral venous blood of rabbits during slow-wave sleep in 1977. The name is slightly misleading — DSIP does not simply knock you out. It modulates sleep architecture, specifically promoting delta wave (stage 3/4 NREM) activity without suppressing REM. That is a very different thing from sedation.
CAS: 62568-57-4. A neuromodulatory peptide that sits at an unusual intersection: sleep science, stress physiology, and pain research, all in one compound.
Mechanism of Action
What makes it odd
DSIP does not fit neatly into any single category. It modulates sleep, but also reduces stress-induced ACTH and cortisol. It has analgesic properties through endogenous opioid facilitation. It affects thermoregulation. And it stimulates LH release, which is a completely different axis. Most peptides do one thing well. DSIP touches five different systems, and nobody has fully explained how a nonapeptide manages that.
Mechanism
Promotes delta wave sleep without suppressing REM — it changes sleep quality, not just sleep quantity. Reduces ACTH and cortisol under stress. Facilitates endogenous opioid activity for analgesic effects. Modulates hypothalamic temperature regulation. Stimulates LH through an unclear pituitary mechanism. The multi-system profile suggests DSIP works upstream of these individual effects, possibly at the level of hypothalamic coordination.
Research Overview
Specs
Molecular weight848.8 Da
CAS62568-57-4
Purity≥98% (supplier batch spec; 99.3% avg across independently tested lots)
FormLyophilized powder
Sizes2mg, 5mg
Storage
Lyophilized at -20°C. Reconstituted: 2-8°C, use within 4 weeks.
Quality
Shipped to a ≥98% supplier batch specification; selected lots are independently tested by Janoshik Analytical (HPLC + mass spectrometry; 99.3% average purity across published reports), searchable by batch code at certapeptides.com/verify. EU QC under CERTALAB S.R.L.
Product Specifications
- Purity: ≥98% (supplier batch spec; 99.3% avg across independently tested lots)
- Form: Lyophilized powder
- SKU: CP-DSIP
Selected lots are independently tested and searchable by batch code. Verify a batch →
For research purposes only. Not for human consumption.
What research shows
Selected peer-reviewed studies from the published literature. Each describes laboratory or preclinical findings and is attributed to the cited study, not to this product. For research use only — not medical guidance.
[1]
Stress response
In rats exposed to restraint stress, delta sleep-inducing peptide (DSIP) was associated with changes in the functional state of hepatocytes in laboratory research.
Effect of Delta Sleep-Inducing Peptide on Functional State of Hepatocytes in Rats During Restraint Stress. Bulletin of Experimental Biology and Medicine (2016). PMID: 26902351[2]
Neuroendocrine stress signalling
In rats with differing resistance to emotional stress, DSIP was studied for its modulation of c-Fos gene expression in the paraventricular nucleus of the hypothalamus in in-vivo research.
Dizocilpine and cycloheximide prevent inhibition of c-Fos gene expression by delta sleep-inducing peptide in the paraventricular nucleus of the hypothalamus in rats with different resistance to emotional stress. Neuroscience Letters (2012). PMID: 22094385[3]
Hippocampal neuronal activity
In rat brain research, DSIP was associated with changes in neuronal activity in the dorsal hippocampus following stimulation of emotion-related brain structures.
Effects of the delta-sleep inducing peptide on neuronal activity in the dorsal hippocampus of rats. Zhurnal Vysshei Nervnoi Deiatelnosti (2013). PMID: 24450167Citations are provided for research reference. CertaPeptides (CERTALAB S.R.L.) is a reseller, not a manufacturer, and makes no medical, therapeutic, or efficacy claims. Products are for laboratory research use only and are not for human or animal consumption.
Researcher Confidence
Why researchers choose CertaPeptides
Who actually tests this?
Selected lots are independently verified by Janoshik Analytical (Czech Republic) and published on the Janoshik public portal. Other lots ship with the supplier's batch specification. See /coa for the published wall.
View COAs →What if I get the wrong batch?
Every bottle label carries a lot number that maps to a specific Certificate of Analysis. If a batch fails spec, we don't ship it — full stop.
View COAs →Where does it ship from?
Romania (EU). We are CERTALAB SRL, CUI 54169956, VAT-registered. Sameday for Romania, GLS for most EU destinations, TCE Worldwide for the remaining cross-border EU and non-EU markets (UK, Switzerland, Norway, Iceland, Israel, Serbia). Delivery 1–15 business days depending on destination — exact window shown at checkout.
Shipping details →What if there's a problem?
You have a 14-day withdrawal right under OUG 34/2014 (Romanian/EU consumer law), with ANPC/ODR escalation available. Contact us at support@certapeptides.com.
Returns policy →Product Information
This product is intended for scientific research and development purposes only. It is a chemical substance that shall not be used as a drug, medicine, active substance, or ingredient in any product intended for human or animal consumption. Researchers must handle this compound in accordance with their institutional biosafety guidelines. Use only in properly equipped laboratory settings with appropriate personal protective equipment.
Frequently Asked
Research Library
Related Research Articles
Frequently researched together
Combined Price
€151.96
DSIP€14.49