Spojina raziskovalne kakovosti. Samo za laboratorijsko uporabo. Ni namenjeno uporabi pri ljudeh ali živalih, zaužitju ali injiciranju. Zdravstvene trditve niso podane niti nakazane.
Čistost ≥98%Dobaviteljeva specifikacija serije · ≥98% (class spec)
Gonadotropic Research PeptidesSKU: CP-TRI2
Triptorelin Acetate 2mg
Čistost ≥98 %Specifikacija dobaviteljeve serije; izbrane serije testirane pri Janoshik
Povezani vnos v PeptidesDB (isti lastnik)
peptidesdb.org
/p/triptorelin
29,99 €Na zalogi
Na zalogi je samo še 10 — naročite kmalu
Dostava v EU v 3-7 delovnih dni
Brezplačna dostava nad €200 · brez carinske dokumentacije (EU) · prek EU carrier network
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Skupaj: 29,99 €
Brezplačna dostava za naročila nad 200 €
Research-grade Triptorelin Acetate. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
Cene glede na količinoSamodejno uporabljeno ob zaključku nakupa
| Količina | Cena na kos | Skupaj | Prihranek |
|---|---|---|---|
| 1 unit | 29,99 € | 29,99 € | -- |
| 3+ | 28,49 € | 85,47 € | 5 % popusta |
| 5+Najbolj priljubljeno | 26,99 € | 134,95 € | 10 % popusta |
| 10+ | 25,49 € | 254,92 € | 15 % popusta |
Pomembno obvestilo
Ta izdelek je namenjen samo za laboratorijsko in raziskovalno uporabo. Ni za uporabo pri ljudeh ali v veterini. Z nakupom potrjujete, da bo ta izdelek uporabljen izključno za in-vitro raziskovalne namene.
Potrebna rekonstitucija
Ta peptid se odpremi liofiliziran (suh prašek) in ga je treba pred uporabo rekonstituirati z bakteriostatsko vodo. Bakteriostatska voda se prodaja ločeno.
Kdaj ta izdelek morda ni primeren za vašo raziskavo
- ⚠Če vaša raziskava zahteva material kakovosti GMP za klinično uporabo — peptidi raziskovalne kakovosti niso namenjeni klinični uporabi.
- ⚠Če vaš laboratorij nima ustreznega hladnega shranjevanja (zamrzovalnik -20 °C) — stabilnost tega peptida je lahko pri višjih temperaturah ogrožena.
- ⚠Če vaš raziskovalni protokol zahteva referenčne standarde, ki jih je odobrila FDA — obrnite se na USP ali ponudnika certificiranega referenčnega materiala.
Čistost HPLC
Povprečna čistost HPLC 99,2 %, preverjena z neodvisnim testiranjem tretje osebe
Testirano pri tretji osebi
Poročilo Janoshik objavljeno, ko je na voljo
Hitra dostava
Odprema v 24 urah, dostava po vsej EU od 4,99 €
Testirano pri tretji osebi
Specifikacija dobaviteljeve serije pri vsakem izdelku; neodvisno poročilo Janoshik za izbrane serije
Zadnji pregled: 2026-07-03
O izdelku Triptorelin Acetate 2mg
Triptorelin is a GnRH agonist analogue -- a synthetic decapeptide with modifications at positions 6 and 10 of the native GnRH sequence that dramatically increase potency and half-life compared to endogenous GnRH. It is FDA- and EMA-approved for prostate cancer, endometriosis, and central precocious puberty under various brand names. Like all long-acting GnRH agonists, it produces an initial "flare" of LH and FSH (and consequently sex steroids) followed by receptor desensitization and profound gonadotropin suppression -- reducing circulating testosterone in men to castrate levels. Each vial contains 2mg.
The mechanism of action is counterintuitive until the receptor biology is understood. GnRH receptors respond to pulsatile stimulation; continuous high-level agonism from a long-acting analogue causes receptor downregulation and uncoupling from intracellular signaling. After 2-4 weeks of continuous exposure, LH and FSH secretion drops dramatically, and consequently so do testosterone and estradiol. This chemical castration is medically equivalent to surgical castration for testosterone-sensitive conditions.
For research applications, triptorelin is used to study GnRH receptor pharmacology, model hypogonadism (chemical castration models), investigate hormone-sensitive tissue biology in the absence of sex steroids, and as a positive control for GnRH agonist effects. The initial flare followed by suppression pattern also makes it useful for timing-controlled endocrine studies.
Specifications
| Parameter | Value |
|---|---|
| Compound | Triptorelin acetate (GnRH agonist analogue) |
| Amount per Vial | 2mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Storage
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 14 days. Protect from light.
Why does a GnRH agonist suppress testosterone rather than increase it?
This is the paradox of GnRH agonist pharmacology. The pituitary GnRH receptor requires pulsatile stimulation to maintain LH and FSH secretion. When triptorelin provides continuous (rather than pulsatile) stimulation due to its long half-life, GnRH receptors become desensitized -- they downregulate and uncouple from signaling. After 2-4 weeks, LH and FSH secretion drops to very low levels, testosterone follows, and the result is chemical castration. The initial "flare" (a brief period of increased LH/FSH/testosterone before desensitization) is clinically important in prostate cancer because it can temporarily worsen symptoms before suppression begins.
How is triptorelin used to create castration models in research?
In animal research, triptorelin (or other long-acting GnRH agonists) administered at sufficient doses produces reliable hypogonadism -- very low testosterone -- without surgical castration. This "chemical castration" model is useful for studying androgen-dependent processes, testing testosterone replacement or alternative therapies, and investigating testosterone's role in specific physiological systems. After cessation of triptorelin treatment, endogenous testosterone production recovers (unlike surgical castration), making chemical castration models reversible -- useful for before/after study designs.
What is the difference between triptorelin, leuprolide, and goserelin?
All three are GnRH agonist analogues with the same fundamental mechanism of GnRH receptor desensitization and gonadotropin suppression. They differ primarily in modification sites, formulation, and half-life. Triptorelin is available as short-acting (daily injection) and long-acting (monthly/3-monthly depot) formulations. Leuprolide is similar with multiple depot options. Goserelin is formulated exclusively as a subcutaneous implant. For research, the short-acting daily-injection form of triptorelin or leuprolide allows better dose control than depot formulations, where the release kinetics add variability.
Triptorelin is supplied for laboratory research use only. Not approved for general human use outside of licensed therapeutic indications. Handle in compliance with institutional biosafety guidelines.
Povzetek specifikacije
Čistost99.2% avg
OblikaLiofiliziran prašek
Shranjevanje-20\u00B0C
O izdelku Triptorelin Acetate 2mg
Triptorelin is a GnRH agonist analogue -- a synthetic decapeptide with modifications at positions 6 and 10 of the native GnRH sequence that dramatically increase potency and half-life compared to endogenous GnRH. It is FDA- and EMA-approved for prostate cancer, endometriosis, and central precocious puberty under various brand names. Like all long-acting GnRH agonists, it produces an initial "flare" of LH and FSH (and consequently sex steroids) followed by receptor desensitization and profound gonadotropin suppression -- reducing circulating testosterone in men to castrate levels. Each vial contains 2mg.
The mechanism of action is counterintuitive until the receptor biology is understood. GnRH receptors respond to pulsatile stimulation; continuous high-level agonism from a long-acting analogue causes receptor downregulation and uncoupling from intracellular signaling. After 2-4 weeks of continuous exposure, LH and FSH secretion drops dramatically, and consequently so do testosterone and estradiol. This chemical castration is medically equivalent to surgical castration for testosterone-sensitive conditions.
For research applications, triptorelin is used to study GnRH receptor pharmacology, model hypogonadism (chemical castration models), investigate hormone-sensitive tissue biology in the absence of sex steroids, and as a positive control for GnRH agonist effects. The initial flare followed by suppression pattern also makes it useful for timing-controlled endocrine studies.
Specifications
| Parameter | Value |
|---|---|
| Compound | Triptorelin acetate (GnRH agonist analogue) |
| Amount per Vial | 2mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Storage
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 14 days. Protect from light.
Why does a GnRH agonist suppress testosterone rather than increase it?
This is the paradox of GnRH agonist pharmacology. The pituitary GnRH receptor requires pulsatile stimulation to maintain LH and FSH secretion. When triptorelin provides continuous (rather than pulsatile) stimulation due to its long half-life, GnRH receptors become desensitized -- they downregulate and uncouple from signaling. After 2-4 weeks, LH and FSH secretion drops to very low levels, testosterone follows, and the result is chemical castration. The initial "flare" (a brief period of increased LH/FSH/testosterone before desensitization) is clinically important in prostate cancer because it can temporarily worsen symptoms before suppression begins.
How is triptorelin used to create castration models in research?
In animal research, triptorelin (or other long-acting GnRH agonists) administered at sufficient doses produces reliable hypogonadism -- very low testosterone -- without surgical castration. This "chemical castration" model is useful for studying androgen-dependent processes, testing testosterone replacement or alternative therapies, and investigating testosterone's role in specific physiological systems. After cessation of triptorelin treatment, endogenous testosterone production recovers (unlike surgical castration), making chemical castration models reversible -- useful for before/after study designs.
What is the difference between triptorelin, leuprolide, and goserelin?
All three are GnRH agonist analogues with the same fundamental mechanism of GnRH receptor desensitization and gonadotropin suppression. They differ primarily in modification sites, formulation, and half-life. Triptorelin is available as short-acting (daily injection) and long-acting (monthly/3-monthly depot) formulations. Leuprolide is similar with multiple depot options. Goserelin is formulated exclusively as a subcutaneous implant. For research, the short-acting daily-injection form of triptorelin or leuprolide allows better dose control than depot formulations, where the release kinetics add variability.
Triptorelin is supplied for laboratory research use only. Not approved for general human use outside of licensed therapeutic indications. Handle in compliance with institutional biosafety guidelines.
Zaupanje raziskovalcev
Zakaj raziskovalci izberejo CertaPeptides
Kdo to dejansko testira?
Izbrane lote neodvisno preverja Janoshik Analytical (Češka) in jih objavi na javnem portalu Janoshik. Drugi loti se odpremijo s specifikacijo dobaviteljeve serije. Objavljeno steno si oglejte na /coa.
Ogled COA →Kaj pa, če dobim napačno serijo?
Vsaka etiketa na steklenički nosi številko lota, ki se ujema z določenim certifikatom o analizi. Če serija ne ustreza specifikaciji, je ne odpremimo — pika.
Ogled COA →Od kod se odpremlja?
Iz Romunije (EU). Smo CERTALAB SRL, CUI 54169956, registrirani za DDV. Sameday za Romunijo, GLS za večino destinacij v EU, TCE Worldwide za preostale čezmejne trge v EU in zunaj EU (Združeno kraljestvo, Švica, Norveška, Islandija, Izrael, Srbija). Dostava 1–15 delovnih dni glede na destinacijo — natančno okno je prikazano ob zaključku naročila.
Podrobnosti o dostavi →Kaj pa, če pride do težave?
Imate 14-dnevno pravico do odstopa po OUG 34/2014 (romunsko/EU potrošniško pravo), z možnostjo eskalacije na ANPC/ODR. Kontaktirajte nas na support@certapeptides.com.
Politika vračil →Podatki o izdelku
Ta izdelek je namenjen izključno znanstvenoraziskovalnim in razvojnim namenom. Gre za kemično snov, ki se ne sme uporabljati kot zdravilo, učinkovina ali sestavina v katerem koli izdelku, namenjenem prehrani ljudi ali živali. Raziskovalci morajo s to spojino ravnati skladno s svojimi institucionalnimi smernicami za biološko varnost. Uporabljajte jo le v ustrezno opremljenih laboratorijskih okoljih z ustrezno osebno zaščitno opremo.
Pogosta vprašanja
Raziskovalna knjižnica
Sorodni raziskovalni članki
Pogosto raziskovano skupaj
Triptorelin Acetate 2mg29,99 €
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