Podarite 15 % popusta in prejmite 10 % povračila za vsako njihovo naročilo.
Spojina raziskovalne kakovosti. Samo za laboratorijsko uporabo. Ni namenjeno uporabi pri ljudeh ali živalih, zaužitju ali injiciranju. Zdravstvene trditve niso podane niti nakazane.
Dostava v EU v 3-7 delovnih dni
Brezplačna dostava nad €200 · brez carinske dokumentacije (EU) · prek EU carrier network
Brezplačna dostava za naročila nad 200 €
Research-grade Adamax. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
| Količina | Cena na kos | Skupaj | Prihranek |
|---|---|---|---|
| 1 unit | 129,99 € | 129,99 € | -- |
| 3+ | 123,49 € | 370,47 € | 5 % popusta |
| 5+Najbolj priljubljeno | 116,99 € | 584,96 € | 10 % popusta |
| 10+ | 110,49 € | 1104,92 € | 15 % popusta |
Pomembno obvestilo
Ta izdelek je namenjen samo za laboratorijsko in raziskovalno uporabo. Ni za uporabo pri ljudeh ali v veterini. Z nakupom potrjujete, da bo ta izdelek uporabljen izključno za in-vitro raziskovalne namene.
Potrebna rekonstitucija
Ta peptid se odpremi liofiliziran (suh prašek) in ga je treba pred uporabo rekonstituirati z bakteriostatsko vodo. Bakteriostatska voda se prodaja ločeno.
Povprečna čistost HPLC 99,2 %, preverjena z neodvisnim testiranjem tretje osebe
Poročilo Janoshik objavljeno, ko je na voljo
Odprema v 24 urah, dostava po vsej EU od 4,99 €
Specifikacija dobaviteljeve serije pri vsakem izdelku; neodvisno poročilo Janoshik za izbrane serije
Adamax is a synthetic neuropeptide fragment based on the vasopressin analogue family, designed with modifications for improved CNS activity and stability. It is used in cognitive neuroscience research, particularly in memory consolidation and retrieval studies. The vasopressin-related peptides have a long history in memory research going back to the 1970s, when DeWied's group showed that vasopressin and its fragments influence avoidance learning and memory in rodents through CNS mechanisms distinct from vasopressin's peripheral endocrine roles (antidiuretic, vasoconstrictor).
Adamax's research context is the posterior pituitary neuropeptide family -- vasopressin (AVP) and oxytocin -- which have extensive CNS projections distinct from their pituitary hormonal release. These neuropeptides modulate hippocampal and amygdalar circuits relevant to memory encoding, social recognition memory, and stress responses. Modified short-chain fragments of vasopressin (like VP4-8, the parent compound of the adamax family) retain memory-influencing properties with reduced peripheral hormonal effects, making them more useful for isolating CNS cognitive effects.
Research applications include spatial and associative memory studies in rodents, investigations into vasopressin system contributions to CNS receptor binding markers, stress-memory interactions, and as a positive control for vasopressin-family peptide research.
| Parameter | Value |
|---|---|
| Compound | Adamax (vasopressin-derived cognitive nootropic peptide) |
| Amount per Vial | 5mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 28 days. Stable lyophilized for 24+ months under proper storage.
The connection between vasopressin and memory originates from work by David DeWied and colleagues in the 1970s-80s, who showed that vasopressin administered peripherally or centrally improved performance in avoidance learning tests in rats, while vasopressin-deficient (Brattleboro) rats showed memory impairments that could be reversed by vasopressin treatment. Subsequent work identified that short fragments of vasopressin (particularly C-terminal fragments like VP4-8) retained memory-facilitating properties without peripheral hormonal effects, suggesting these effects were mediated by CNS receptors. This research tradition led to development of modified fragments like those in the adamax family.
Vasopressin V1a receptors are expressed in the hippocampus, amygdala, septum, and other limbic structures involved in memory encoding and consolidation. Vasopressin acts as a neuromodulator in these circuits, influencing synaptic plasticity and the encoding of emotionally significant or aversive events. It enhances memory consolidation for avoidance tasks and influences social recognition memory through amygdala V1a signaling. The stress-memory interaction is also relevant: vasopressin release during stress may help encode stress-related memories, which connects vasopressin research to PTSD-related neuroscience.
Common tasks include passive avoidance (one-trial learning with a foot shock), active avoidance, Morris water maze (spatial memory), novel object recognition, and social recognition memory. These tasks have established sensitivity to vasopressin-system interventions. The passive avoidance test is particularly associated with the DeWied vasopressin memory literature because vasopressin fragments robustly improve retention in this paradigm. For researchers studying memory peptides, choosing the appropriate behavioral assay for the memory system of interest (hippocampus-dependent, amygdala-dependent, etc.) is important for interpretable results.
Adamax is supplied for laboratory research use only. Not approved for human use. Handle in compliance with institutional biosafety guidelines.
Adamax is a synthetic neuropeptide fragment based on the vasopressin analogue family, designed with modifications for improved CNS activity and stability. It is used in cognitive neuroscience research, particularly in memory consolidation and retrieval studies. The vasopressin-related peptides have a long history in memory research going back to the 1970s, when DeWied's group showed that vasopressin and its fragments influence avoidance learning and memory in rodents through CNS mechanisms distinct from vasopressin's peripheral endocrine roles (antidiuretic, vasoconstrictor).
Adamax's research context is the posterior pituitary neuropeptide family -- vasopressin (AVP) and oxytocin -- which have extensive CNS projections distinct from their pituitary hormonal release. These neuropeptides modulate hippocampal and amygdalar circuits relevant to memory encoding, social recognition memory, and stress responses. Modified short-chain fragments of vasopressin (like VP4-8, the parent compound of the adamax family) retain memory-influencing properties with reduced peripheral hormonal effects, making them more useful for isolating CNS cognitive effects.
Research applications include spatial and associative memory studies in rodents, investigations into vasopressin system contributions to CNS receptor binding markers, stress-memory interactions, and as a positive control for vasopressin-family peptide research.
| Parameter | Value |
|---|---|
| Compound | Adamax (vasopressin-derived cognitive nootropic peptide) |
| Amount per Vial | 5mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 28 days. Stable lyophilized for 24+ months under proper storage.
The connection between vasopressin and memory originates from work by David DeWied and colleagues in the 1970s-80s, who showed that vasopressin administered peripherally or centrally improved performance in avoidance learning tests in rats, while vasopressin-deficient (Brattleboro) rats showed memory impairments that could be reversed by vasopressin treatment. Subsequent work identified that short fragments of vasopressin (particularly C-terminal fragments like VP4-8) retained memory-facilitating properties without peripheral hormonal effects, suggesting these effects were mediated by CNS receptors. This research tradition led to development of modified fragments like those in the adamax family.
Vasopressin V1a receptors are expressed in the hippocampus, amygdala, septum, and other limbic structures involved in memory encoding and consolidation. Vasopressin acts as a neuromodulator in these circuits, influencing synaptic plasticity and the encoding of emotionally significant or aversive events. It enhances memory consolidation for avoidance tasks and influences social recognition memory through amygdala V1a signaling. The stress-memory interaction is also relevant: vasopressin release during stress may help encode stress-related memories, which connects vasopressin research to PTSD-related neuroscience.
Common tasks include passive avoidance (one-trial learning with a foot shock), active avoidance, Morris water maze (spatial memory), novel object recognition, and social recognition memory. These tasks have established sensitivity to vasopressin-system interventions. The passive avoidance test is particularly associated with the DeWied vasopressin memory literature because vasopressin fragments robustly improve retention in this paradigm. For researchers studying memory peptides, choosing the appropriate behavioral assay for the memory system of interest (hippocampus-dependent, amygdala-dependent, etc.) is important for interpretable results.
Adamax is supplied for laboratory research use only. Not approved for human use. Handle in compliance with institutional biosafety guidelines.
Zaupanje raziskovalcev
Kdo to dejansko testira?
Izbrane lote neodvisno preverja Janoshik Analytical (Češka) in jih objavi na javnem portalu Janoshik. Drugi loti se odpremijo s specifikacijo dobaviteljeve serije. Objavljeno steno si oglejte na /coa.
Ogled COA →Kaj pa, če dobim napačno serijo?
Vsaka etiketa na steklenički nosi številko lota, ki se ujema z določenim certifikatom o analizi. Če serija ne ustreza specifikaciji, je ne odpremimo — pika.
Ogled COA →Od kod se odpremlja?
Iz Romunije (EU). Smo CERTALAB SRL, CUI 54169956, registrirani za DDV. Sameday za Romunijo, GLS za večino destinacij v EU, TCE Worldwide za preostale čezmejne trge v EU in zunaj EU (Združeno kraljestvo, Švica, Norveška, Islandija, Izrael, Srbija). Dostava 1–15 delovnih dni glede na destinacijo — natančno okno je prikazano ob zaključku naročila.
Podrobnosti o dostavi →Kaj pa, če pride do težave?
Imate 14-dnevno pravico do odstopa po OUG 34/2014 (romunsko/EU potrošniško pravo), z možnostjo eskalacije na ANPC/ODR. Kontaktirajte nas na support@certapeptides.com.
Politika vračil →Ta izdelek je namenjen izključno znanstvenoraziskovalnim in razvojnim namenom. Gre za kemično snov, ki se ne sme uporabljati kot zdravilo, učinkovina ali sestavina v katerem koli izdelku, namenjenem prehrani ljudi ali živali. Raziskovalci morajo s to spojino ravnati skladno s svojimi institucionalnimi smernicami za biološko varnost. Uporabljajte jo le v ustrezno opremljenih laboratorijskih okoljih z ustrezno osebno zaščitno opremo.