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≥98% grynumasTiekėjo partijos specifikacija · ≥98% (class spec)
Gonadotropic Research PeptidesSKU: CP-TRI2
Triptorelin Acetate 2mg
≥98% grynumasTiekėjo partijos specifikacija; atrinktos partijos tirtos Janoshik
Susijęs PeptidesDB įrašas (tas pats savininkas)
peptidesdb.org
/p/triptorelin
29,99 €Yra sandėlyje
Sandėlyje liko tik 10 — užsakykite netrukus
Pristatoma į EU per 3-7 darbo dienos
Nemokamas pristatymas viršijus €200 · jokių muitinės dokumentų (ES) · su EU carrier network
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Iš viso: 29,99 €
Nemokamas siuntimas užsakymams virš €200
Research-grade Triptorelin Acetate. 99.3% avg purity, HPLC & MS verified. Lyophilized powder in sealed glass vial. For laboratory research use only. Not for human consumption.
Kainos pagal kiekįTaikoma automatiškai atsiskaitant
| Kiekis | Kaina už vienetą | Iš viso | Sutaupymas |
|---|---|---|---|
| 1 unit | 29,99 € | 29,99 € | -- |
| 3+ | 28,49 € | 85,47 € | 5% nuolaida |
| 5+Populiariausia | 26,99 € | 134,95 € | 10% nuolaida |
| 10+ | 25,49 € | 254,92 € | 15% nuolaida |
Svarbi pastaba
Šis produktas skirtas tik laboratoriniam ir tyrimų naudojimui. Ne vartoti žmonėms ar veterinarinei paskirčiai. Pirkdami patvirtinate, kad šis produktas bus naudojamas išimtinai in vitro tyrimų tikslais.
Reikia atskiedimo
Šis peptidas siunčiamas liofilizuotas (sausi milteliai) ir prieš naudojimą jį reikia atskiesti bakteriostatiniu vandeniu. Bakteriostatinis (BAC) vanduo parduodamas atskirai.
Kada šis produktas gali netikti Jūsų tyrimui
- ⚠Jei Jūsų tyrimui reikalinga GMP klasės medžiaga klinikiniam taikymui — tyrimų klasės peptidai nėra skirti klinikiniam naudojimui.
- ⚠Jei Jūsų laboratorija neturi tinkamų šalto saugojimo sąlygų (-20°C šaldiklio) — šio peptido stabilumas aukštesnėje temperatūroje gali sumažėti.
- ⚠Jei Jūsų tyrimo protokolui reikalingi FDA patvirtinti pamatiniai standartai — kreipkitės į USP arba sertifikuotos pamatinės medžiagos tiekėją.
Grynumas HPLC
99,2% vidutinis HPLC grynumas, patvirtintas nepriklausomo trečiosios šalies tyrimo
Tirta trečiosios šalies
Janoshik ataskaita skelbiama, kai tampa prieinama
Greitas siuntimas
Išsiuntimas per 24 val., siuntimas visoje ES nuo €4.99
Tirta trečiosios šalies
Tiekėjo partijos specifikacija kiekvienam produktui; nepriklausoma Janoshik ataskaita atrinktoms partijoms
Paskutinį kartą peržiūrėta: 2026-07-03
Apie Triptorelin Acetate 2mg
Triptorelin is a GnRH agonist analogue -- a synthetic decapeptide with modifications at positions 6 and 10 of the native GnRH sequence that dramatically increase potency and half-life compared to endogenous GnRH. It is FDA- and EMA-approved for prostate cancer, endometriosis, and central precocious puberty under various brand names. Like all long-acting GnRH agonists, it produces an initial "flare" of LH and FSH (and consequently sex steroids) followed by receptor desensitization and profound gonadotropin suppression -- reducing circulating testosterone in men to castrate levels. Each vial contains 2mg.
The mechanism of action is counterintuitive until the receptor biology is understood. GnRH receptors respond to pulsatile stimulation; continuous high-level agonism from a long-acting analogue causes receptor downregulation and uncoupling from intracellular signaling. After 2-4 weeks of continuous exposure, LH and FSH secretion drops dramatically, and consequently so do testosterone and estradiol. This chemical castration is medically equivalent to surgical castration for testosterone-sensitive conditions.
For research applications, triptorelin is used to study GnRH receptor pharmacology, model hypogonadism (chemical castration models), investigate hormone-sensitive tissue biology in the absence of sex steroids, and as a positive control for GnRH agonist effects. The initial flare followed by suppression pattern also makes it useful for timing-controlled endocrine studies.
Specifications
| Parameter | Value |
|---|---|
| Compound | Triptorelin acetate (GnRH agonist analogue) |
| Amount per Vial | 2mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Storage
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 14 days. Protect from light.
Why does a GnRH agonist suppress testosterone rather than increase it?
This is the paradox of GnRH agonist pharmacology. The pituitary GnRH receptor requires pulsatile stimulation to maintain LH and FSH secretion. When triptorelin provides continuous (rather than pulsatile) stimulation due to its long half-life, GnRH receptors become desensitized -- they downregulate and uncouple from signaling. After 2-4 weeks, LH and FSH secretion drops to very low levels, testosterone follows, and the result is chemical castration. The initial "flare" (a brief period of increased LH/FSH/testosterone before desensitization) is clinically important in prostate cancer because it can temporarily worsen symptoms before suppression begins.
How is triptorelin used to create castration models in research?
In animal research, triptorelin (or other long-acting GnRH agonists) administered at sufficient doses produces reliable hypogonadism -- very low testosterone -- without surgical castration. This "chemical castration" model is useful for studying androgen-dependent processes, testing testosterone replacement or alternative therapies, and investigating testosterone's role in specific physiological systems. After cessation of triptorelin treatment, endogenous testosterone production recovers (unlike surgical castration), making chemical castration models reversible -- useful for before/after study designs.
What is the difference between triptorelin, leuprolide, and goserelin?
All three are GnRH agonist analogues with the same fundamental mechanism of GnRH receptor desensitization and gonadotropin suppression. They differ primarily in modification sites, formulation, and half-life. Triptorelin is available as short-acting (daily injection) and long-acting (monthly/3-monthly depot) formulations. Leuprolide is similar with multiple depot options. Goserelin is formulated exclusively as a subcutaneous implant. For research, the short-acting daily-injection form of triptorelin or leuprolide allows better dose control than depot formulations, where the release kinetics add variability.
Triptorelin is supplied for laboratory research use only. Not approved for general human use outside of licensed therapeutic indications. Handle in compliance with institutional biosafety guidelines.
Specifikacijų santrauka
Grynumas99.2% avg
FormaLiofilizuoti milteliai
Laikymas-20\u00B0C
Apie Triptorelin Acetate 2mg
Triptorelin is a GnRH agonist analogue -- a synthetic decapeptide with modifications at positions 6 and 10 of the native GnRH sequence that dramatically increase potency and half-life compared to endogenous GnRH. It is FDA- and EMA-approved for prostate cancer, endometriosis, and central precocious puberty under various brand names. Like all long-acting GnRH agonists, it produces an initial "flare" of LH and FSH (and consequently sex steroids) followed by receptor desensitization and profound gonadotropin suppression -- reducing circulating testosterone in men to castrate levels. Each vial contains 2mg.
The mechanism of action is counterintuitive until the receptor biology is understood. GnRH receptors respond to pulsatile stimulation; continuous high-level agonism from a long-acting analogue causes receptor downregulation and uncoupling from intracellular signaling. After 2-4 weeks of continuous exposure, LH and FSH secretion drops dramatically, and consequently so do testosterone and estradiol. This chemical castration is medically equivalent to surgical castration for testosterone-sensitive conditions.
For research applications, triptorelin is used to study GnRH receptor pharmacology, model hypogonadism (chemical castration models), investigate hormone-sensitive tissue biology in the absence of sex steroids, and as a positive control for GnRH agonist effects. The initial flare followed by suppression pattern also makes it useful for timing-controlled endocrine studies.
Specifications
| Parameter | Value |
|---|---|
| Compound | Triptorelin acetate (GnRH agonist analogue) |
| Amount per Vial | 2mg |
| Purity | 99.3% avg (HPLC verified) |
| Format | Lyophilized powder |
| Reconstitution | Sterile water or saline |
| Storage | -20°C; 2-8°C after reconstitution |
Storage
Store at -20°C before reconstitution. Refrigerate at 2-8°C after reconstitution and use within 14 days. Protect from light.
Why does a GnRH agonist suppress testosterone rather than increase it?
This is the paradox of GnRH agonist pharmacology. The pituitary GnRH receptor requires pulsatile stimulation to maintain LH and FSH secretion. When triptorelin provides continuous (rather than pulsatile) stimulation due to its long half-life, GnRH receptors become desensitized -- they downregulate and uncouple from signaling. After 2-4 weeks, LH and FSH secretion drops to very low levels, testosterone follows, and the result is chemical castration. The initial "flare" (a brief period of increased LH/FSH/testosterone before desensitization) is clinically important in prostate cancer because it can temporarily worsen symptoms before suppression begins.
How is triptorelin used to create castration models in research?
In animal research, triptorelin (or other long-acting GnRH agonists) administered at sufficient doses produces reliable hypogonadism -- very low testosterone -- without surgical castration. This "chemical castration" model is useful for studying androgen-dependent processes, testing testosterone replacement or alternative therapies, and investigating testosterone's role in specific physiological systems. After cessation of triptorelin treatment, endogenous testosterone production recovers (unlike surgical castration), making chemical castration models reversible -- useful for before/after study designs.
What is the difference between triptorelin, leuprolide, and goserelin?
All three are GnRH agonist analogues with the same fundamental mechanism of GnRH receptor desensitization and gonadotropin suppression. They differ primarily in modification sites, formulation, and half-life. Triptorelin is available as short-acting (daily injection) and long-acting (monthly/3-monthly depot) formulations. Leuprolide is similar with multiple depot options. Goserelin is formulated exclusively as a subcutaneous implant. For research, the short-acting daily-injection form of triptorelin or leuprolide allows better dose control than depot formulations, where the release kinetics add variability.
Triptorelin is supplied for laboratory research use only. Not approved for general human use outside of licensed therapeutic indications. Handle in compliance with institutional biosafety guidelines.
Tyrėjų pasitikėjimas
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Kas iš tikrųjų tai tiria?
Atrinktas serijas nepriklausomai patikrina Janoshik Analytical (Čekija), o rezultatai skelbiami viešame Janoshik portale. Kitos serijos siunčiamos su tiekėjo partijos specifikacija. Paskelbtų rezultatų sieną žr. /coa.
Peržiūrėti COA →Kas, jei gausiu ne tą partiją?
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Peržiūrėti COA →Iš kur siunčiama?
Iš Rumunijos (ES). Esame CERTALAB SRL, CUI 54169956, registruoti PVM mokėtoju. Sameday Rumunijoje, GLS daugumai ES krypčių, TCE Worldwide likusioms tarpvalstybinėms ES ir ne ES rinkoms (JK, Šveicarijai, Norvegijai, Islandijai, Izraeliui, Serbijai). Pristatymas 1–15 darbo dienų priklausomai nuo krypties – tikslus terminas rodomas atsiskaitymo metu.
Siuntimo informacija →Kas, jei kils problema?
Turite 14 dienų teisę atsisakyti sutarties pagal OUG 34/2014 (Rumunijos/ES vartotojų teisės aktus), su galimybe kreiptis į ANPC/ODR. Susisiekite su mumis adresu support@certapeptides.com.
Grąžinimo politika →Produkto informacija
Šis produktas skirtas tik moksliniams tyrimams ir plėtrai. Tai cheminė medžiaga, kurios negalima naudoti kaip vaisto, vaistinio preparato, veikliosios medžiagos ar sudedamosios dalies jokiame produkte, skirtame žmonėms ar gyvūnams vartoti. Tyrėjai privalo tvarkyti šį junginį laikydamiesi savo institucijos biosaugos gairių. Naudokite tik tinkamai įrengtose laboratorijose su atitinkamomis asmeninėmis apsaugos priemonėmis.
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Triptorelin Acetate 2mg29,99 €
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